Other

Kuraray Co., Ltd.

Yoshimi Kakimaru

Masao Tanihara

Takashi Makabe

Mitsuo Tsukamoto

Tatsuhiko Higaki

Mototsugu Saishin

Takumi Fujitani

The invention relates to an ocular tissue regeneration inducer which comprises, as an active ingredient, a hydrophilic polymer mainly composed of alkylene glycol units or vinyl monomeric units having a nondissociating hydrophilic group. The composition can induce the regeneration of ocular tissues such as the cornea, the crystalline lens, and the vitreous body.

Ocular tissue regeneration inducer

Provided is a medical material useful for wound dressings or a drug delivery system, which material is safe and has high healing effects, more specifically, which is free from cytotoxicity or other side effects caused by a drug and permits the selective healing of the diseased site in a small dosage without damaging the sites other than the diseased site. The medical material so provided is a polymer gel having a sequence represented by the formula: A-Sp1-E-Sp2-G wherein A represents a water-swelling polymer gel, Sp1 represents the first spacer, E represents a cleavable group with the main chain to be cleaved via an enzymatic reaction, Sp2 represents the second spacer and G represents a drug. When the polymer gel is used, the cleavable group (E) is cleaved according to an amount of an enzyme existing at the diseased site to release the drug in accordance with the amount of the enzyme.

Polymer gel for medical use

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Kurashiki, Japan

Yoshimi Kakimaru