Fujifilm Corporation

Yoshiki Sakazaki

Toshihiro Usa

Kenichiro Tamaki

Ikuo Takano

Satoshi Wakamatsu

Keio Okano

Yuka Kobayashi

Soft mold transfer container

Soft mold transfer container lid

The present invention provides a microneedle array, a support member, a method of producing a microneedle array, and a microneedle array unit which enable reduction of a drying time during production and prevention of breakage during drying. Provided are a microneedle arrayincluding a sheet portion, a plurality of needle-like protrusions, and a support memberformed of a gripping portionand a beam portionhaving one end that is connected to the gripping portion, in which the sheet portionis an integrally molded body which is integrally molded with the support member, in which at least a part of the beam portionis buried under the other surfaceof the sheet portion, opposite to the one surface where the needle-like protrusionsare provided, the gripping portionis provided on the other surfaceof the sheet portion, and the beam portionis deformable toward a center of the sheet portion. Further, provided are the support member, a method of producing the microneedle array, and a microneedle array unitincluding a container

Microneedle array, support member, method of producing microneedle array, and microneedle array unit

Provided is a method of manufacturing a microneedle array in which an active ingredient is concentrated at a tip while an active ingredient content is guaranteed. In order to achieve the object, a method of manufacturing a microneedle array in which needle-like recessed portions of a mold are filled with a liquid to form one dose of a patch includes determining a filling amount of the liquid from a difference in mass of the mold before and after filling of the liquid, determining a filling state of the liquid in the mold filled with the liquid, sucking the mold in which the filling amount and the filling state of the liquid are determined to be normal from a rear face, and evaporating and drying a solvent of the liquid of the sucked mold.

Method of manufacturing microneedle array

Provided are a storage container, a microneedle unit, a storage container group, and a method of producing a microneedle unit that enable protection of a microneedle array before puncture and realization of a puncturing property of the microneedle array using a simple member. The storage container, which stores a microneedle array including a sheet having a first surface and a second surface that oppose each other and a plurality of needles arranged on the first surface of the sheet, includes a first member having an edge portion that defines a second opening and a second member having a depression, in which the microneedle array is stored by superimposing the second member on the first member, and the second member and the first member are deformed by applying a force to the second member in a state in which the second member is superimposed on the first member, and the needles of the microneedle array are allowed to protrude from the first member to puncture a skin.

Storage container, microneedle unit, storage container group, and method of producing microneedle unit

Provided are a mold case that prevents deformation of a microneedle array, and a manufacturing method of a microneedle array. The problems are solved by the manufacturing method of a microneedle array including: a filling step of filling needle-like recessed portions of a mold having flexibility and having a plurality of the needle-like recessed portions on a front surface, with a liquid material; and a drying step of drying the liquid material in a state where the mold filled with the liquid material is stored in the mold case which causes an edge portion of the mold to be sandwiched between the lid and the pedestal.

Mold case and manufacturing method of microneedle array

Case for injecting microneedle array

A background image is acquired by imaging an opening plate as a background of an original document in a state where the original document is not arranged. Next, an original document including background image is acquired by imaging the same range as the background image in a state where the original document is arranged on an upper surface of the opening plate. Next, a difference image is generated by subtracting the background image from the original document including background image. In addition, an inverse difference image is generated by subtracting the original document including background image from the background image. A region of the original document is detected based on the difference image and the inverse difference image.

Original document detection apparatus and original document detection method

A bonding target object and a film including a layer having lower toughness than the bonding target object are disposed between a set of pressurization molds, which have pressurization surfaces disposed so as to face each other and in which opening holes are formed in the pressurization surfaces. A first edge on the opening hole side of the pressurization surface of a first pressurization mold, out of the set of pressurization molds, which faces the film is positioned further inside the opening hole than a second edge on the opening hole side of the pressurization surface of a second pressurization mold which faces the bonding target object. The pressing target portion of the film which is pressed by the set of pressurization molds is bonded to the bonding target object by sandwiching the bonding target object and the film with the set of pressurization molds to be pressed.

Bonding method and device

A sheet bonding device includes a pressurization mold which is constituted of an upper mold and a lower mold and performs sealing through heating by sandwiching a sealing target portion of a bag main body and a sealing target portion of a gas barrier function sheet with pressurization surfaces; a plurality of support pins which are provided in the lower mold so as to be retractable and position the gas barrier function sheet with respect to one surface of the bag main body by penetrating the sealing target portions of the bag main body and the gas barrier function sheet; and gas spray means for making the gas barrier function sheet float by spraying inert gas to an area-enlarged portion, which does not overlap the bag main body, of the gas barrier function sheet supported by the support pins.

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Kanagawa, Japan

Yoshiki Sakazaki