Texmac, Inc.

Nano Device and System Research Inc.

Yoshikazu Tobinaga

Susumu Sugiyama

An applicator for applying functional substances, such as cosmetic powder, food color marking, India ink effect marks, or drugs into human skin, having a base, a plurality of microneedles fixed to and projecting from the base a distance only sufficient to penetrate into the stratum corneum or dermis, with the microneedles being of a material that is capable of disintegration and dispersion into the stratum corneum or dermis, such as maltose. The needles contain the functional substance for delivery into the stratum corneum or dermis. The microneedles are of a length approximately 0.5 to 500 &#x3bc;m when used to apply a functional substance to the stratum corneum, or are of a length of approximately 500 to 5,000 &#x3bc;m when used to apply a functional substance to the dermis.

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Shiga, Japan

Yoshikazu Tobinaga