Other

Kyocera Corporation

Mochida Pharmaceutical Co., Ltd.

Tazuke Kofukai

Daido Tokushuko Kabushiki Kaisha

Yoshihisa Suzuki

Masao Tanihara

Yoshihiko Nishimura

Mitsuko Isaji

Shinobu Takagi

Masaki Shinkawa

Hiroaki Yoshida

Yasushi Kaneta

Yangdong Zhan

Provided is a non-tubular brain damage recovery material which is used to cover and/or fill a damaged part of the brain, the brain damage recovery material including: (A) a cross-linked body with which a bioabsorbable polysaccharide having a carboxyl group in a low endotoxin molecule is covalently bonded and cross-linked with at least one crosslinking reagent selected from among a compound represented by general formula (I) and salts thereof; and (B) a bioabsorbable polymer. RHN—(CH)—NHR(I) [in the formula, Rand Reach independently represent a hydrogen atom or a group represented by formula of —COCH(NH)—CH]—NH, and n represents an integer from 2 to 18]. Accordingly, provided is a medical material which can recover a damaged part of the brain.

Brain damage recovery material

A concrete durability protection method is provided, including following steps: Step one: rinsing the concrete surface; Step two: spraying agent A material or alternately spraying agent B material and agent A material at the wet surface of the concrete; Step three: repeating step two. The beneficial effects of the present invention include: nanoscale active silicate penetrates into the concrete surface layer within a certain depth and reacts with free calcium ions within the concrete to form C&#x2014;S&#x2014;H crystalline, thereby improving the compactness of the concrete surface layer within a certain depth, repairing defects in the concrete surface layer within a certain depth, such as the capillary interstices, pores, microcracks, etc., so as to effectively improve the durability of concrete. The unreacted nanoscale active silicate material has permanent activity. It could recover its activity when the concrete absorbs moisture, and continue to react with free calcium ions in the concrete to quickly form C&#x2014;S&#x2014;H crystals, realizing the permanent concrete durability protection.

Nano modified silicate capillary crystalline material and use method thereof

A non-tubular material for nerve regeneration induction, which can be used for the regeneration of a damaged part in a nerve, and which comprises: (A) a crosslinked form produced by crosslinking a low-endotoxin bioabsorbable polysaccharide having a carboxyl group in the molecule with at least one crosslinkable reagent selected from a compound represented by general formula (I) and a salt thereof via covalent bonds; and (B) a bioabsorbable polymer. RHN&#x2014;(CH)&#x2014;NHR(I) [wherein Rand Rindependently represent a hydrogen atom or a group represented by formula: &#x2014;COCH(NH)&#x2014;(CH)&#x2014;NH, and n represents an integer of 2 to 18]. Thus, a medical material that can induce the regeneration of a damaged part in a nerve is provided.

Nerve regeneration-inducing material

A peptide has at least an amino acid sequence represented by SEQ ID NO:1 and it has an osteogenetic activity.

Peptide having osteogenetic activity and osteogenetic accelerator containing the same

A peptide has any one of the sequences SEQ ID NO.1 to SEQ ID NO.8, or has a sequence derived from any one of the sequences SEQ ID NO.1 to SEQ ID NO.8 by substitution, deletion or addition of one or several amino acids therein and having an osteogenetic activity.

Growing community of inventors

Sakyo-ku, Kyoto-shi Kyoto, Japan

Yoshihisa Suzuki