Hokkaido University

Fujifilm Corporation

National Institute of Advanced Industrial Science and Technology

Japan Science and Technology Agency

Fujirebio Inc.

Yoshihiro Sakoda

Hiroshi Kida

Koichi Mukasa

Takayoshi Oyamada

Nobuyuki Fujii

Kazuhisa Sueoka

Kazuhiko Matsumoto

Yoshiaki Uchida

Koji Kuruma

Makoto Sawamura

Hirotaka Hosoi

Takashi Shirakawa

Seiji Takeda

Atsushi Ishii

Toshio Shimada

Eiji Miyagawa

Hiroyuki Kogaki

Agus Subagyo

Provided is a microneedle. The microneedle array includes a needle portion, which contains an inactivated whole virion influenza vaccine, and a sheet portion. Also provided is an administration method in which the microneedle array is administered and then administered secondly after an interval of equal to or greater than 24 hours and less than 2 months.

Inactivated whole virion vaccine-containing microneedle array preparation and method for administering the same

A method of immunoassay of H5 subtype influenza A virus by which the virus can be accurately assayed even in cases where a certain level of mutation has occurred in the H5 subtype influenza A virus, and a kit therefor, and a novel anti-H5 subtype influenza A virus monoclonal antibody which can be used for the immunoassay are disclosed. The antibody or an antigen-binding fragment thereof of the present invention undergoes antigen-antibody reaction with hemagglutinin of H5 subtype influenza A virus, and the corresponding epitope of the antibody or an antigen-binding fragment thereof is located in a region other than the receptor subdomain (excluding C-terminal region thereof consisting of 11 amino acids), which antibody or an antigen-binding fragment thereof does not have neutralizing activity against the influenza A virus.

Anti-(influenza a virus subtype H5 hemagglutinin) monoclonal antibody

A single-electron transistor comprising at least a substrate, a source electrode and a drain electrode formed on top of the substrate opposing to each other, and a channel arranged between the source electrode is disclosed wherein the channel is composed of ultra fine fibers. By having such a constitution, a sensor can have excellent sensitivity.

Single-electron transistor, field-effect transistor, sensor, method for producing sensor, and sensing method

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Sapporo, Japan

Yoshihiro Sakoda