Public University Corporation Yokohama City University

Kabushiki Kaisha Toshiba

Ricoh Company, Ltd.

Osaka University

Nagoya University

Toshiba Energy Systems & Solutions Corporation

Tosoh Corporation

National University Corporation Yokohama National University

Yoshihiro Ishikawa

Masanari Umemura

Taisuke Akimoto

Kazuhito Kishi

Motokazu Hasegawa

Fumihito Arai

Masami Takai

Masataka Akaishi

Shinya Sakuma

Hajime Koyama

Hideyuki Kawajiri

Norihisa Ohtake

Seiichi Inoue

Makoto Kaneko

Noriaki Arakawa

Utako Yokoyama

Yukito Yada

Satoshi Okumura

Yujiro Hoshino

Hiroki Kobori

Munetaka Masuda

Tomoaki Ishigami

Shin-Ichi Suzuki

Inoue Seiichi

A power supply apparatus includes a power supply configured to apply an alternating current to a magnetic field generation apparatus; and a controller configured to control the alternating current applied by the power supply. The controller controls the power supply to apply the alternating current having a waveform pattern including a plurality of current waveforms having different frequency spectrums from each other.

Power supply apparatus and magnetic field generation system

A cancer treatment apparatus including a magnetic field generator that generates a magnetic field of 100 kHz to 300 kHz to be applied to affected tissues.

Cancer treatment apparatus

In a guide vane according to an embodiment of the invention, where in a section perpendicular to a guide vane rotation axis, a curvature of a contour line forming a runner side vane surface of the guide vane is referred to as a positive curvature when the contour line is formed to be convex, while the curvature of the contour line is referred to as a negative curvature when the contour line is formed to be concave, a negative curvature portion where the curvature of the contour line becomes negative is provided on the runner side vane surface. The negative curvature portion is formed from an upper end portion to a lower end portion of the runner side vane surface.

Guide vane and fluid machine

Means which enables preparation of a thick cell aggregate by a simple process without an operation of detaching and stacking of cells is disclosed. The method for preparing a three-dimensional cell aggregate by the present invention comprises: a cell encasing step of placing a cell suspension in a cell container; and a pressure application step of applying pressure to cells in the container. The cell encasing step and the pressure application step may be carried out a plurality of times. By the present invention, a thick, robust cell aggregate can be obtained by a simple operation of applying pressure to a cell suspension or a medium containing cells. Since the method does not require an operation of stacking a plurality of cell sheets, the cells are hardly damaged, and the conditions of the cells can be favorably maintained, so that the cells can be advantageously used as a tissue piece for transplantation.

Method for producing three-dimensional cell aggregates

The present invention provides a novel compound capable of inhibiting cardiac adenylyl cyclase. The present invention relates to a compound represented by the following formula (I) or a pharmaceutically acceptable salt, ester or solvate thereof: where R, Rand Reach independently represent a hydrogen atom or an acyl group having an acidic or basic substituent, provided that all of R, Rand Rare not simultaneously a hydrogen atom. The present invention also provides a modulator of adenylyl cyclase activity, a pharmaceutical composition and a food composition, all of which comprise the above-described compound or a pharmaceutically acceptable salt, ester or solvate thereof.

Modulator of activity of adenylate cyclase

Growing community of inventors

Yokohama, Japan

Yoshihiro Ishikawa