Fujisawa Pharmaceutical Company, Ltd.

Yoshie Sakamoto

Takao Takaya

Hisashi Takasugi

Atsushi Kuno

Hiroyoshi Sakai

Kazuhiro Maeda

Kimio Esumi

The invention relates to a pharmaceutical composition as a therapeutic agent for ischemic disease comprising a compound of the formula ##STR1## wherein R.sup.1 is carbamoyl substituted with morpholino (lower) alkyl, thiomorpholino(lower)alkyl or lower alkylamino(lower)alkyl; or ureido substituted with lower alkylamino(lower)alkyl; and

N-containing heterocyclic compounds, and composition comprising the same

An N-containing heterocyclic compound of the formula: ##STR1## wherein R.sup.1 is lower alkyl optionally substituted with hydroxy, halogen or a heterocyclic group, carboxy, esterified carboxy, carbamoyl optionally substituted with heterocyclic(lower)alkyl or lower alkylamino(lower)alkyl, N-containing heterocycliccarbonyl optionally substituted with lower alkyl, or ureido optionally substituted with lower alkylamino(lower)alkyl, and

Morpholine containing pyridine compounds, compositions and use

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Yonago, Japan

Yoshie Sakamoto