Fujirebio Inc.

Kabushiki Kaisha Toshiba

Hokkaido University

Yoshiaki Uchida

Yoshihiro Kurano

Kazuya Omi

Takuya Sakyu

Takashi Shirakawa

Satoru Ito

Nobuyuki Fujii

Hiroshi Ohashi

Masahiro Kusunoki

Masami Sugiyama

Tetsuji Tanimoto

Aiko Tanaka

Yoshihiro Sakoda

Hiroshi Kida

Tsuyoshi Ando

Katsutoshi Goishi

Koichi Koyama

Hiroshi Ishikawa

Asako Oka

Takafumi Uchida

Eiji Miyagawa

Hiroyuki Kogaki

The present invention provides a method of measuring a vitamin D. Specifically, the present invention provides a method of measuring a vitamin D, comprising: (1) treating a sample with a surfactant having a steroid skeleton; and (2) detecting the vitamin D in the treated sample. The present invention also provides a kit for measuring a vitamin D, comprising: (1) a surfactant having a steroid skeleton; and (2) an affinity substance for a vitamin D and/or a vitamin D standard. Examples of the surfactant having the steroid skeleton may include a bile acid or a derivative thereof or a salt thereof.

Vitamin D measurement method and measurement kit

The present invention provides a means and a method for specifically measuring a substance such as a small substance with high sensitivity by a sandwich method. Specifically, the present invention provides an antibody capable of specifically binding to an affinity complex and a method of measuring of the affinity complex comprising measuring the affinity complex using the antibody capable of specifically binding to the affinity complex. The antibody of the present invention may be a full-length antibody. The antibody of the present invention may also have a region derived from an immunoglobulin from an animal having an ability of gene conversion (e.g., a complementarity-determining region, a framework region, or a variable region). Examples of at least one factor that constitutes the affinity complex include a small substance or a protein (e.g., antibody).

Antibody against affinity complex

A method of immunoassay of H5 subtype influenza A virus by which the virus can be accurately assayed even in cases where a certain level of mutation has occurred in the H5 subtype influenza A virus, and a kit therefor, and a novel anti-H5 subtype influenza A virus monoclonal antibody which can be used for the immunoassay are disclosed. The antibody or an antigen-binding fragment thereof of the present invention undergoes antigen-antibody reaction with hemagglutinin of H5 subtype influenza A virus, and the corresponding epitope of the antibody or an antigen-binding fragment thereof is located in a region other than the receptor subdomain (excluding C-terminal region thereof consisting of 11 amino acids), which antibody or an antigen-binding fragment thereof does not have neutralizing activity against the influenza A virus.

Anti-(influenza a virus subtype H5 hemagglutinin) monoclonal antibody

A novel monoclonal antibody which specifically binds to apo-B-48 is disclosed. The monoclonal antibody specifically binds to apo-B-48 but does not bind to apo-B-100.

Anti-APO-B-48 monoclonal antibody, hybridoma producing the same, and method for measuring APO-B-48 using the same

Anti-apo-B-48 monoclonal antibody, hybridoma producing the same, and method for measuring apo-B-48 using the same

A method for simply measuring a 1,2-dicarbonyl derivative in multiple specimens is provided, which comprises converting a 1,2-dicarbonyl derivative to a pyrazine derivative represented by the formula (I):

Antibody that recognizes pyrazine derivative and method for measuring 1,2-dicarbonyl derivative using said antibody

A method for measuring glycated hemoglobin is disclosed, which comprises contacting a sample with an anti-hemoglobin antibody being bound to a solid phase, adding thereto an anti-glycated hemoglobin antibody, and then measuring the anti-glycated hemoglobin antibody bound to the solid phase via glycated hemoglobin and the anti-hemoglobin antibody. A method for measuring glycated hemoglobin is further disclosed, which comprises mixing a sample with particles on which an anti-glycated hemoglobin antibody is bound to cause immunoagglutination reaction. A method for measuring glycated hemoglobin is furthermore disclosed, which comprises mixing a sample with a solution containing a monoclonal antibody specific for glycated hemoglobin, and then measuring the change in the turbidity of the resulting mixture. A method is disclosed for measuring glycated hemoglobin which comprises mixing a sample with unsensitized latex particles and an anti-glycated hemoglobin antibody, to cause immunoagglutination reaction. There is disclosed a method for measuring glycated hemoglobin which comprises mixing a sample with unsensitized latex particles and particles on which an anti-glycated hemoglobin antibody is bound, to cause immunoagglutination reaction. Still furthermore, an anti-glycated hemoglobin monoclonal antibody having a high specificity for human glycated hemoglobin is disclosed.

Anti-glycated hemoglobin monoclonal antibody and method for measuring

A phenytoin derivative represented by formula (I) ##STR1## wherein Ph denotes a phenyl group,

Phenytoin derivatives

A magnetic recording apparatus capable of efficiently erasing data in accordance with a type of magnetic recording medium, comprises a current source, an erase head for erasing data recorded on a recording medium using a supplied erase current, and a current supplying section for supplying an erase current from the current source to the erase head in accordance with input erase current control data. The current supplying section comprises a selecting section for selecting a combination of a plurality of control elements in accordance with the input erase current control data, and a supplying section for supplying an erase current determined in accordance with the selected combination from the current source to the erase head.

Method of efficiently erasing data in accordance with type of magnetic

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Tokyo, Japan

Yoshiaki Uchida