Zeria Pharmaceutical Co., Ltd.

Mitsubishi Mining and Cement Co. Ltd.

Mitsubishi Materials Corporation

H. Lundbeck A/s

Yoshiaki Tanaka

Kazuyasu Hikita

Naoki Nakata

Tomoji Aotsuka

Naoyoshi Miura

Motoki Torizuka

Kuniyoshi Ogura

Naomi Kobayashi

Hisayoshi Kato

Hiroyuki Iizuka

Heihachiro Arai

Harumi Kanai

Akihiro Okubo

Mitsuo Soeda

Mikiya Ono

Kenji Uchino

Yugo Ikeda

Hiroyasu Nishioka

Tadashi Mori

Noaki Nakata

Hikaru Morita

Itaru Yamaguchi

Tadashi Kurimoto

Hikari Morita

Cholinesterase activator

Arylalkanoylamine derivative and drug containing the same

A method for the treatment of dementia and cerebrovascular disorders and for inhibiting platelet aggregation in patients in need thereof comprising the step of administering a therapeutically effective amount of a 1-[3-(dimethylamino)propyl]-1-phenylphthalane of the general formula ##STR1## wherein R.sup.1 and R.sup.2 each are selected from the group consisting of halogen, trifluoromethyl, cyano and R--CO--, wherein R is an alkyl radical, or a pharmaceutically-acceptable acid addition salt thereof, is described.

Treatment of cerbrovascular disorders

An optical switch for use as a shutter for intercepting or passing light signals, such as beam lights, including a piezoelectric actuator attached at one end thereof to a base plate and at its other end to an optical shielding object for intercepting or passing over light beams, a mirror installed on a location close to the place where the piezoelectric actuator is attached to the base plate to reflect passed light beams, and the piezoelectric actuator being coupled to a source of energy. The light signals are intercepted or passed by the movement of the object due to modifications of the piezoelectric actuator, and the passed light signals are reflected by the mirror and detected by an optical detector.

Optical switch with piezoelectric bimorph

An optical scanner for scanning light signals, such as light beams, including an electrostrictive element attached at one end thereof to a base body, a convex mirror fixed to the other end of the electrostrictive element, a driving circuit for changing a voltage applied to the electrostrictive element, and an emitter for emitting a light beam to the surface of the convex mirror in a direction different from the modified direction of the electrostrictive element. When the applied voltage to the electrostrictive element changes by the driving circuit during reflecting light beams on the convex mirror surface, the electrostrictive element is modified according to the applied voltage. Simultaneously light beams are scanned over a wide range, even if the modified volume is small, due to continuous change of deflection angles of beams according to the radius of the curvature of the convex mirror.

Optical scanner

A photo-driven optical deflecting apparatus in which a light beam is deflected by using only light beam(s), comprising (a) a dielectric substrate having 'photovoltaic effect'; (b) one or more first couples of electrodes formed in or on at least a portion of the surface(s) of said substrate so as to polarize the portion(s) positioned between said couple(s) of the electrodes formed thereby; (c) one or more photo-driving or photo-receiving elements provided at least in the polarized portion(s) of the surface of said dielectric substrate, having a polarization direction oriented in one direction, and having photovoltaic effect so as to generate a voltage between said electrodes; (d) a dielectric and transparent prism having 'electrooptic effect' through which a light beam to be deflected is passed and deflected, provided on the surface of said substrate, having a second couple of electrodes provided on a couple of the surfaces of the prism, which surfaces are parallel to the optic axis; and a polarizer provided on the surface through which said beam enters; (d) leads electrically connecting said first electrodes to said second electrodes; the light beam to be deflected enters through said polarizer into said prism through which the light beam passes to be deflected; and said prism being operated directly by the photovoltage generated by said photo-driving element(s).

Photo-driven light beam deflecting apparatus

Phenylalkanoylamine derivatives, process for preparing the same, and

A piezoelectric transducer having electrodes formed on both surfaces has a piezoelectric base molded as a curved plate which can converge sound fields of acoustic waves at an arbitrary point and which can reduce noise or reverberation in a lateral direction which otherwise occur due to unnecessary vibration. At least one of the electrodes is divided concentrically. A material having a small electromechanical coupling factor K.sub.p in the lateral direction is used for the piezoelectric material, preferably porous PZT.

Piezoelectric transducer

A piezoelectric transducer having plural piezoelectric transducer elements which can generate mechanical vibrations converging substantially on one point. The transducer is formed to control the convergent point by insulating piezoelectric transducer elements mechanically, arranging them concentrically and driving them independently and separately from each other.

Novel condensed benzene derivatives having prolyl endopeptidase inhibitory, anti-hypoxic, and anti-amnesic activities are disclosed. The compounds are represented by the following (I), ##STR1## wherein A represents a methylene, ethylene, or propylene group, B represents a methylene or ethylene group, m denotes an integer of 0-5, X and Y, which may be same or different, individually represent a methylene group or sulfur atom, R.sup.1 represents a hydrogen atom, a carboxyl, lower alkyloxycarbonyl, hydroxymethyl, or formyl group, R.sup.2 represents a hydrogen atom, a halogen atom, a lower alkyl, lower alkoxy, nitro, or amino group, R.sup.3 represents a hydrogen atom or a lower alkyl group, and the dotted line may optionally be present. They are useful as a medicine for treating or preventing cerebral circulation disorder, cerebral metabolism disorder, or memory disturbance.

Condensed benzene derivative

Novel N-substituted amino acid imide derivatives are disclosed. The compounds are represented by formula (I): ##STR1## wherein n represents an integer of 0 to 5, and X and Y, which may be the same or different, represent a methylene group or a sulfur atom, provided that not both X and Y are methylene groups at the same time. The compounds are useful as a medicine for treating or preventing cerebral circulation disorder, cerebral metabolism disorder, or memory disturbance.

Amino acid imide derivatives, usage thereof, and medicinal composition

Growing community of inventors

Saitama, Japan

Yoshiaki Tanaka