Human Metabolome Technologies, Inc.

Other

Sysmex Corporation

Gyokikai Medical Corporation

Kawamura, Noriyuki

Yoshiaki Ohashi

Hajime Sato

Takushi Ohga

Noriyuki Kawamura

Kosaku Shinoda

Takamasa Ishikawa

Yasuhiro Otomo

Kazunori Sasaki

Kouzou Suto

Tamaki Fujimori

Hiroyuki Yamamoto

Kumi Yamaki

To provide a method for simply measuring ethanolamine phosphate in a sample, and a reagent, kit, program and the like useful in the method. A measurement method of ethanolamine phosphate includes a first step of adding an enzyme, which can catalyze a reaction that forms acetaldehyde from ethanolamine phosphate, to a sample, and conducting a first enzymatic reaction to form acetaldehyde, phosphoric acid and ammonia; and a second step of quantifying at least one of the resultant acetaldehyde, phosphoric acid and ammonia to determine an amount of the ethanolamine phosphate in the measurement sample.

Method for measuring ethanolamine phosphate

A method for treating depression using a biomarker includes measuring a level of phosphoethanolamine in a blood sample collected from a subject, comparing the level of phosphoethanolamine in the blood sample with a predetermined threshold, in response to the level of phosphoethanolamine in the blood sample being below the predetermined threshold, determining that the subject requires a treatment for depression, and treating the subject determined to suffer from depression.

Biomarker of depression, method for measuring biomarker of depression, computer program, and recording medium

Provided is a method for using low molecular weight compounds found in the body as a biomarker for diagnosing depression. Specifically, more than one compound selected from a group comprising the following are used: ADP-ribose, ATP, ADP, AMP, serotonin, tryptophan, kynurenine, SDMA (symmetrical dimethylarginine), threonine, glyceric acid, serine, N-acetylaspartic acid, glutamic acid, trigonelline, creatine, 2-methylserine, sphingosine, homovanillic acid, piperidine, sulfoxidized methionine, pipecolic acid, sphinganine, gamma-butyrobetaine, guanidinoacetic acid, isobutyric acid, creatinine, sarcosine, 3-methylbutyric acid, nicotinamide, betaine, ornithine, carnitine, ethanolamine, phosphoethanolamine, taurine, hypotaurine, aspartic acid, methionine, and tyrosine.

Biomarker for depression, method for measuring a biomarker for depression, computer program, and recording medium

The present invention relates to novel diagnostic markers for kidney disease and the use thereof.

Diagnostic marker for kidney diseases and use thereof

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Tsuruoka, Japan

Yoshiaki Ohashi