Taisei Kako Co., Ltd.

Nihon Tengantaku Kenkyusyo Co., Ltd.

Nihon Tenganyaku Kenkyusyo Co., Ltd.

Other

Nihon Tenganyaku Kenkyusho Co., Ltd.

Yorihisa Uetake

Hirokazu Mihashi

Seiji Yoshimura

Yasuyuki Shiraishi

Keiji Hamamoto

Teruo Nishida

Masaru Otsuka

Kenji Matsuura

Kazuya Iwahashi

Kazuko Suzuki

Shinji Matsuda

Hidetoshi Kondo

Hiroaki Iwata

Norio Hoshi

A plug member integrally includes a base portion () attached to a plug holder () to be mounted on a mouth portion of a container, a plug () engaged with an engagement portion () provided in an outlet passage of the plug holder (), and a resilient connection portion () resiliently connecting the plug () to the base portion (). Before the first use, the outlet passage is closed with the plug member. In the first use, the container is squeezed to increase the internal pressure of the container. Thus, the plug () is disengaged from the engagement portion () by the internal pressure. The outlet passage is thereafter constantly kept open.

Mouth cap for liquid container

A filtering discharge container employing a delaminatable bottle was provided, which reliably prevents a content liquid from leaking out before the first use, and reduces a discharging resistance during the second and subsequent use. An engagement portion () is provided in an outlet passage of a mouth cap (). A plug () is engaged with the engagement portion () in such a manner that the plug () can be disengaged from the engagement portion () by an internal pressure of an inner layer bag () increased by squeeze-deforming a body of an outer layer bottle (). The outlet passage is closed with the plug () engaged with the engagement portion (). After the plug () is disengaged from the engagement portion (), liquid communication is established between the inside of the inner layer bag () and a filter ().

Filtering discharge container

In a filtering dispenser container which includes a plug attached to a mouth portion of a bottle thereof and having a liquid discharge passage, and a filter and a check valve provided in the discharge passage, air lock is prevented, even if the container contains a highly percolative liquid, by preventing a very small amount of liquid percolating the check valve from reaching the filter. In the filtering dispenser container, a dam () is provided between the check valve () and the filter () for retaining a very small amount of the liquid percolating the check valve () when the check valve is closed. Thus, the filter () is prevented from being wetted with the liquid percolating the closed check valve () during storage or delivery of the container before the first use of the container.

Filtering dispenser container

An object is to find the minimum activity expression site of fibronectin, clarify the actions of this minimum unit in relation to opthalmological fields, and provide an opthalmological composition having this minimum unit as an effective component. This invention provides an opthalmological composition, in particular, a corneal disorder treatment agent containing the peptide, PHSRN (SEQ ID NO: 1) (Pro-His-Ser-Arg-Asn (SEQ ID NO: 1)), or Ac-Pro-His-Ser-Arg-Asn-NH, which is a derivative thereof, or a salt thereof that is allowable as a medical drug as an effective component. The preferred dosage form is an ophthalmic formulation.

Ophthalmological composition

A filter-equipped container which, particularly in a small-sized eyedrop bottle or the like, is capable of accurate dropping while preventing bubbles from being involved when a contents liquid is to be delivered through a delivery port. To solve such problem, a plug bodydisposed in the mouth of a bottleis provided with a delivery passage for delivering contents liquid received in the bottle, the delivery passage being provided with a filter. The filteris composed of a filter filmfor filtering bacteria to prevent the latter from permeating from upstream to downstream as seen in the direction of delivery, and a contents liquid holding memberof porous material that has microscopic pores, disposed upstream of the filter film, the contents liquid holding memberbeing in planar contact with the filter film

Container with a filter

Discharging container with a filter and a bottle stopper for use in the container

Growing community of inventors

Aichi, Japan

Yorihisa Uetake