Accuragen Holdings Limited

Yontao Lu

Malek Faham

Shengrong Lin

Li Weng

Zhaohui Sun

Ling Fung Tang

Yingyu Wang

In some aspects, the present disclosure provides methods for identifying sequence variants, as well as methods of determining copy number of a genetic locus in a sample. Systems and kits for performing methods of the disclosure, as well as compositions produced by or useful in methods of the disclosure are also provided. In some embodiments, methods comprise extending 3' ends of polynucleotides by adding one or more pre-determined nucleotides. In some embodiments, methods comprise use of a strand-tagging sequence.

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Sunnyvale, CA, United States of America

Yontao Lu