Zhejiang University

Xiamen Biotime Biotechnology Co., Ltd.

Yongqiang Shi

Yong He

Xuping Feng

Mingzhu Tao

Shifeng Liu

Rui Yang

Zhiyong Yu

Jinnuo Zhang

Lei Lin

Fangfang Qu

A compound represented by formula (I) and a pharmaceutical composition thereof. The compound represented by formula (I) can be used as an adenosine receptor inhibitor, in particular, A2A and/or A2B inhibitors, for example, can be used for preventing or treating diseases related to A2A and/or A2B activity or expression level.

Adenosine receptor antagonist

A digital detection method and system for predicting drug resistance of transgenic maize are disclosed. The method includes acquiring an RGB image, three-dimensional point cloud data and chlorophyll relative content of a maize plant after medicament spraying at a current moment; calculating a pixel ratio and morphological feature according to the RGB image and three-dimensional point cloud data; inputting a detection parameter of the maize plant at the current moment into a series model to predict the detection parameter of the maize plant at a next moment to obtain a graph of change in the detection parameter in a next period; estimating a drug resistance characteristic according to the graph of the change in the detection parameter of the maize plant; and inputting the detection parameter of the maize plant at the current moment into a parallel model to predict the variety of the maize plant.

Digital detection method and system for predicting drug resistance of transgenic maize

The present disclosure provides a ratiometric fluorescent probe, a preparation method thereof, and an application in detection of hydrogen peroxide. In the present disclosure, MoOQDs (nanoenzymes) and Co/Zn-MOFs both have catalytic activity, and the large specific surface area and porous structure of Co/Zn-MOFs can provide more binding sites for the contact between nanoenzymes and substrates. Moreover, Co/Zn-MOFs have high catalytic activity similar to natural enzymes. When nanoenzymes with fluorescent properties encounter Co/Zn-MOFs with similar catalytic activity, they will collide with a spark of 'synergy catalysis', and the fusion of the two plays a role of synergy catalysis; in addition, the uniform cavity of Co/Zn-MOFs can provide 'hosts' for nanoenzymes, and Co/Zn-MOFs provide &#x201c;anchors&#x201d; for MoOQDs, avoiding the aggregation of MoOQDs and enhancing the stability of the probe.

Ratiometric fluorescent probe, preparation method thereof, and application in detection of hydrogen peroxide

Growing community of inventors

Hangzhou, China

Yongqiang Shi