P2 Science, Inc.

Basf Se Corporation

Symrise Ag

Yonghua Yang

Patrick Foley

Tania Salam

Yong Tu

Robert Bedoukian

Thomas Killinger

Ralf Pelzer

Ashoke Bhattacharjee

Bernd Hölscher

Johannes Panten

Alexander Kendall

The present invention relates to bi- and tricyclic compounds of the general formula (I) (I) wherein the dashed lines independently of each other represent a single or a double bond, X represents a group of the formulae Xto Xwherein the asterisk denotes the point of attachment to the rest of the molecule, Rand R, independently of each other, are selected from hydrogen or methyl, or Rtogether with Rform a methylene or ethylene group, R, R, R, R, Rand R, independently of each other, are selected from hydrogen or methyl, Ris selected from hydrogen, methyl or ethyl, and Ris methyl or ethyl, to a method of preparing said compounds, to the use of a bi- or tricyclic compounds or of mixtures of two or more bi- and tricyclic compounds or of a stereoisomer thereof or of a mixture of two or more stereoisomers thereof as aroma chemicals; to the use of a bi- or tricyclic compound for modifying the scent character of a fragranced composition; to an aroma chemical composition containing a bi- or tricyclic compound or a mixture of two or more bi- and tricyclic compounds or of a stereoisomer thereof or of a mixture of two or more stereoisomers thereof; and to a method of preparing a fragranced composition or for modifying the scent character of a fragranced composition, comprising incorporating a bi- or tricyclic compound or a mixture of two or more bi- and tricyclic compounds or of a stereoisomer thereof or of a mixture of two or more stereoisomers thereof into said composition.

Bi- and tricyclic compounds for use as aroma chemicals

The invention contemplates certain polyethers, polyether derivatives, and methods of making and using those same polymers. For example, the starting materials can, e.g., citronellol, prenol, isocitronellol and isoprenol.

Polyether derivatives, uses, and methods of making the same

The present disclosure pertains to a new synthetic method for the preparation of 2-methyl-2-hydroxyheptane and 2-methyl-2-alkoxyheptanes, which are valuable commodities for use in flavors, fragrances and various personal care products, such as cosmetics.

Method for synthesis of 2-methyl-2-hydroxyheptane and 2-methyl 2-alkoxyheptanes

The present disclosure pertains to new methods of performing a hydrodealkenylation of monounsaturated alcohols, thiols, and derivatives thereof, such as terpenes and derivatives, comprising ozonolysis and quenching using a sulfinic acid or sulfinic acid salt.

Methods for hydrodealkenylation

The present disclosure provides improved methods of performing ozonolysis on alkenes comprising non-reductive quenching of ozonide intermediates using Bronsted bases to yield aldehyde, ketone and/or carboxylic acid products.

Methods for disproportionation quenching of ozonides

A method for producing slcareolide comprising the following steps: (a) providing sclareol as starter material; (b) contacting the starter material sclareol with ozone in air or oxygen as the sole oxidant in an acidic medium.

Method for producing sclareolide

The present invention relates to the synthesis of intermediate compounds which can be used in the synthesis of mint lactone and related compounds, including 3,6-dimethylhexahydrobenzofuran-2-ones, isomers, and other derivatives.

Preparation of 3-hydroxy-3,6-dimethylhexahydrobenzofuran-2-one and derivatives thereof

The invention is directed to methods of producing alkoxylated or hydroxylated terpenes comprising the steps of continuously passing a solution comprising an alcohol in combination with a terpene over an acidic resin catalyst in a packed bed reactor in order to yield a product, as well as compounds that are the products of the methods described herein.

Methods for the continuous alkoxylation and derivatization of terpenes

Preparation of 3-hydroxy-3,6- dimethylhexahydrobenzofuran-2-one and derivatives thereof

The present application relates to the preparation of cyclohexyl-alkyl carbinols, including 1-(cyclohex-3-en-1-yl)-2-methylpropan-1-ol, which possesses a minty aroma that can be described as fresh, invigorating, and menthol-like, and also possesses cooling properties. The use of cyclohexyl-alkyl carbinols as readily accessible and cost effective fragrance, flavor, and cooling ingredients, and potential applications thereof is also described.

Olfactive compositions comprising cyclohexyl-alkyl carbinols

The present invention relates to uses of vanadium to convert aldehydes and ozonides into their respective acids and/or ketones. More particularly, this invention relates to the oxidative work-ups following ozonolysis using vanadium during ozonolysis, and using vanadium to oxidize aldehydes in general. The invention also relates to methods comprising the ozonolysis of oleyl alcohol in the presence of either an acid or an alcohol.

Growing community of inventors

New Haven, CT, United States of America

Yonghua Yang