Commonwealth Scientific and Industrial Research Organisation

Yonggang Zhu

Stephen Charles Trowell

Helen Dacres

Murat Gel

Nan Wu

Nam Cao Hoai Le

Guy Parker Metcalfe

Richard Manasseh

Paul Mun Foo Tho

The present invention relates to methods and systems for detecting one or more analytes in a sample and/or for classifying a sample. In particular, the present invention relates to methods and systems which can be used to detect the analytes in real time and which rely on flowing through a microfluidic device one or more types of sensor molecule each comprising a domain that binds one or more analytes, a chemiluminescent donor domain and an acceptor domain, wherein the separation and relative orientation of the chemiluminescent donor domain and the acceptor domain, in the presence and/or the absence of analyte, is within &#xb1;50% of the Forster distance.

Methods and systems for detecting an analyte or classifying a sample

The present invention relates to methods and systems for detecting one or more analytes in a sample and/or for classifying a sample. In particular, the present invention relates to methods and systems which can be used to detect the analytes in real time and which rely on flowing through a microfluidic device one or more types of sensor molecule each comprising a domain that binds one or more analytes, a chemiluminescent donor domain and an acceptor domain, wherein the separation and relative orientation of the chemiluminescent donor domain and the acceptor domain, in the presence and/or the absence of analyte, is within +50% of the Forster distance.

A method of mixing (), including: providing a fluid () in a well () so as to establish an acoustic field gradient; and applying an acoustic signal to cause mixing within a fluid ().

Method for microfluidic mixing and mixing device

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Mentone, Australia

Yonggang Zhu