Indiana University

Cedars-sinai Medical Center

Yong Yue

Yi Zhang

Described herein is a peptide, a multimodal peptide ligand imaging agent and methods for use in tumor targeting, tumor visualization, drug delivery and as an imaging ligand. The invention further provides for a theranostic peptide agent and methods for use in the treatment of cancer and/or inflammation in a subject.

Peptide compositions for immuno-oncology molecular imaging and targeted drug delivery

MRI for radiotherapy simulation, planning and/or treatment guidance requires accurate motion assessment and real-time tumor monitoring. Clinical image-guided radiotherapy requires precise quality assurance of targeted tumor geometry and motion phase and amplitudes for both MRI and CT images. In various embodiments, the MRI-CT compatible phantom described herein is designed to validate the accuracy and performance of clinical procedures in both a 4D MRI sequence and 4D CT imaging, and to provide equivalent dynamic image contrast and quality for both imaging modalities. Additionally described is a PET compatible phantom.

Growing community of inventors

Los Angeles, CA, United States of America

Yong Yue