Other

Qualcomm Incorporated

Tolero Pharmaceuticals, Inc.

California Institute of Technology

Supergen, Inc

Sumitomo Dainippon Pharma Oncology, Inc.

The Rockefeller University

Sumitomo Pharma Oncology, Inc.

Astex Pharmaceuticals, Inc.

Yong Xu

Koc-Kan Ho

Xiaohui Liu

Michael David Saunders

David J Bearss

Hariprasad Vankayalapati

Farrukh Aquil

Boris Andreev

Kenneth Mark Parnell

Jihua Liu

Steven G Kultgen

Jason Marc Foulks

Kevin Bret Wright

Benjamin Gary Brenning

Scott Albert Pearce

Steven Brian Kanner

David Lee Vollmer

Michael Xu

Peter W Yohi

Douglas Cruise

Vikas Mahendiyan

Axel Scherer

Yu-Chong Tai

Amnon Yariv

John O'Brien

Vaishnav Srinivas

Mahalingam Nagarajan

Xiao-Hui Liu

Ravindra Arvind Khedkar

Vincent A Fischetti

William Alexander Denny

Nan Chen

Zhiqin Chen

Fukang Jiang

Jeffrey Mark Hinrichs

Sanjeev Redkar

Pasit Phiasivongsa

Patrick Isakanian

Chang Ki Kwon

Satish Krishnamoorthy

Michael Thomas Fertsch

Anand Meruva

Joon Young Park

Krzysztof Swierczek

Zeeshan Shafaq Syed

Swarna Gamage

Darby Brooke

Charles Erec Stabbins

Chuan-cheng Cheng

Chaun-cheng Cheng

Yuxin Li

Vishal Mishra

Micheal David Saunders

Dave Bearss

Charles Erec Stebbins

In some aspects, an electronic device may receive a clock signal having a first frequency. The electronic device may receive, for a chip select training operation, a chip select signal having a pattern including high pulses and low pulses. The electronic device may perform, for a sampling window, the chip select training operation using the clock signal and the chip select signal, wherein the sampling window includes a quantity of pulses of the chip select signal. The electronic device may provide, via a first data in or out (DQ) pin, an indication of a first result of the chip select training operation for the high pulses of the chip select signal. The electronic device may provide, via a second DQ pin, an indication of a second result of the chip select training operation for the low pulses of the chip select signal. Numerous other aspects are described.

Enhanced chip select signal training

A memory interface circuit includes a first receiver coupled to a differential data strobe signal and a second receiver that has a first input coupled to a reference voltage source and a second input coupled to one of the pair of complementary signals. A qualification circuit is configured to detect a preamble transmission in the differential data strobe signal based on timing provided by an output of the first receiver when the memory interface circuit is in a first operating state, detect the preamble transmission in the differential data strobe signal based on timing provided by an output of the second receiver when the memory interface circuit is in a second operating state, and assert a preamble detection signal when the preamble transmission is detected. A gating circuit is configured to provide a receive clock signal when the preamble detection signal is asserted.

Read data capture for a high-speed double data rate interface

A memory interface circuit has a first differential receiver having a first input coupled to a first reference voltage source, a second differential receiver configured to receive a differential data strobe signal in a pair of complementary signals, a third differential receiver having a first input coupled to a second reference voltage source and a second input configured to receive one of the pair of complementary signals, a clock generation circuit configured to generate a read clock signal based on an output of the second differential receiver and using a qualifying signal output by the third differential receiver to qualify one or more edges in the read clock signal and a data capture circuit clocked by the read clock signal and configured to capture data from the output of the first differential receiver using the one or more edges in the read clock signal.

Clock qualifier enhancement for external double data rate memory interfaces

A method for clock switching includes propagating a first clock signal through a first clock path, propagating a second clock signal through a second clock path, generating a first delay control signal based on the first clock signal, and generating a second delay control signal based on the second clock signal. The method also includes, in a first mode, coupling the first clock path to a delay circuit and inputting the first delay control signal to a control input of the delay circuit. The method also includes, in a second mode, coupling the second clock path to the delay circuit and inputting the second delay control signal to the control input of the delay circuit.

DDR phy parallel clock paths architecture

Methods and apparatuses for improve clocking scheme to reduce power consumption are presented. The apparatus includes a host configured to communicate with a memory via a link. The host is further configured to receive a first clock from the memory; to receive, based on the first clock, data from the memory, in a first mode of a read operation; to generate a second clock, the second clock being generated independent of the first clock; and to receive, based on the second clock, data from the memory, in a second mode of the read operation.

Clocking scheme to receive data

Signal timing drift in a synchronous dynamic random access memory (SDRAM) system may be compensated for by performing write signal timing training using a multi-purpose command (MPC) first-in-first-out (FIFO) write and MPC FIFO read at periodic intervals interspersed with mission-mode SDRAM traffic. The test result samples obtained from the write signal timing training may be analyzed independently of mission-mode SDRAM traffic. The mission-mode timing of the SDRAM data bit signals relative to the SDRAM write clock signal may be adjusted based on the analysis.

System and method for compensating for SDRAM signal timing drift through periodic write training

The present invention provides a compound having the following structure: Compositions and methods for using the same in the treatment of skin disorders and other Pim kinase-associated conditions are also disclosed.

Substituted imidazo[1,2-B]pyridazines as protein kinase inhibitors

Compounds having activity as PKM2 activators are disclosed. The compounds have the following structure (I): including stereoisomers, tautomers, pharmaceutically acceptable salts and prodrugs thereof, wherein R, R, R, R, Rand Rare as defined herein. Methods associated with preparation and use of such compounds, as well as pharmaceutical compositions comprising such compounds, are also disclosed.

PKM2 modulators and methods for their use

The present invention provides substituted imidazo[1,2-b]pyridazines that are useful as protein kinase inhibitors and have one of the following structures (I), (II) or (III): or a stereoisomer, prodrug, tautomer or pharmaceutically acceptable salt thereof, wherein R, R, Rand X are as defined herein. For example, a compound having the following structure:  Compositions and methods for using the same in the treatment of cancer, autoimmune, inflammatory and other Pim kinase-associated conditions are also disclosed.

The present invention is intended to provide a LED light that could display brilliant heart shape rainbow-like lighting effects and offer flexible casing structure for easily extending the hardware capability. It has case and circuit board. The circuit board has Micro Control Unit (MCU), LED chips, micro push buttons and power supply module, etc. The LED chips are electrically connected to the MCU via an output power amplifier module. The micro push buttons are electrically connected to the MCU, and the power supply module offers DC power to the circuit board. Characterized in that: the said case includes ring-shaped plates and end panels which seal one end of the rings; the circuit board is embedded in the inner wall of the surrounding ring-shaped plate; the micro push buttons are soldered on the circuit board and the tops of the micro push buttons extended out of the top panel; the LED chips are located inside the case; the ring-shaped plates and the end panels are made of transparent material; the width along the radial direction is not the same along the circumferential direction of the ring-shaped plate of the case.

Kind of LED light

The present invention provides protein kinase having one of the following structures (I), (II) or (III): or a stereoisomer, prodrug, tautomer or pharmaceutically acceptable salt thereof, wherein R, R, Rand X are as defined herein. Compositions and methods for using the same in the treatment of cancer, autoimmune, inflammatory and other Pim kinase-associated conditions are also disclosed.

Provided is a new method for preparing PARP inhibitor talazoparib.

Synthesis of PARP inhibitor talazoparib

Provided is a new method for preparing (E)-3-(4-methoxyphenyl)-N-methyl-N-((6,7,8,9-tetrahydro-5H-benzo[7]annulen-2-yl)methyl)prop-2-en-1-amine as a drug intermediate.

Process preparing of (E)-3-(4-methoxyphenyl)-N-methyl-N-((6,7,8,9-tetrahydro-5H-benzo-[7]annulen-2-yl)methyl)prop-2-en-1-amine

Growing community of inventors

Midvale, UT, United States of America

Yong Xu