Sequenom, Inc.

Washington University

Agena Bioscience, Inc.

Yong Qing Chen

Mathias Ehrich

Cosmin Deciu

Ron Michael McCullough

Roger Chan Tim

Guy Del Mistro

Dirk Johannes Van Den Boom

Akos Vertes

Christiane Honisch

Ron Michael Mccullough

Provided are methods for identifying the presence or absence of a chromosome abnormality by which a cell-free sample nucleic acid from a subject is analyzed. In certain embodiments, provided are methods for identifying the presence or absence of a fetal chromosome abnormality in a nucleic acid from cell-free maternal blood.

Processes and kits for identifying aneuploidy

The present invention provides a method of producing a laser-patterned silicon surface, especially silicon wafers for use in laser desorption ionization (LDI-MS) (including MALDI-MS and SELDI-MS), devices containing the same, and methods of testing samples employing the same. The surface is prepared by subjecting a silicon substrate to multiple laser shots from a high-power picosecond or femtosecond laser while in a processing environment, e.g., underwater, and generates a remarkable homogenous microcolumn array capable of providing an improved substrate for LDI-MS.

Laser desorption ionization and peptide sequencing on laser induced silicon microcolumn arrays

Growing community of inventors

San Diego, CA, United States of America

Yong Qing Chen