Bioapplications Inc.

Republic of Korea (Animal and Plant Quarantine Agency)

Postech Academy-Industry Foundation

Yong Jik Lee

Eun Ju Sohn

Inhwan Hwang

Sangmin Lee

Kyung Min Min

Jae-Young Song

In Hwan Hwang

Hyang Ju Kang

Jae Yoon Kim

In-Ohk Ouh

Soo Dong Cho

Hye Young Jeoung

Beong Sul Kang

Dong Jun An

Nam Hyung Kim

Ha-Hyun Kim

Dong-Kun Yang

Nam Jo Park

Seyeon Park

Seong In Lim

Per-Olof Berggren

Sung Min Gu

Yun Joo Yoo

Jae Young Song

Soo Hong Park

The present invention relates to: a rabies virus glycoprotein comprising an amino acid sequence represented by SEQ ID NO: 2; a recombinant vector for producing the glycoprotein; a transformant comprising the vector; and a vaccine composition comprising the rabies glycoprotein, and the like.

Vaccine composition for preventing rabies, and preparation method thereof

A recombinant vector for transforming a plant, a plant transformed with the recombinant vector, a plant-made classical swine fever virus antigen pmE2 protein expressed in the plant and uses thereof is provided. By using a recombinant vector having a polynucleotide encoding a GP55 protein of CSFV according to the present invention; and a polynucleotide encoding a cellulose-binding domain protein; and a plant transformed with the recombinant vector, a plant-made classical swine fever virus antigen pmE2 protein may be produced with high efficiency, and has higher safety and stability than those achieved by other production methods. Also, since the plant-derived classical swine fever virus antigen protein pmE2 has a cellulose-binding domain (CBD) protein, it may be usefully used as an effective marker to determine a virus exposure pathway and an antibody producing pathway.

Vaccine composition for classical swine fever from plant and manufacturing method thereof

The present invention provides a plant expressing a target protein, a method of preparing the same and a method of preparing a composition for oral administration of a biopharmaceutical using the same. A target protein expression system using plant cells according to the present invention solves conventional problems in plant cell culture, provides a method of producing a large quantity of target proteins including a biopharmaceutical protein and allowing a target protein to have a resistance to a protease present in a digestive organ, and therefore is very effective to enable commercialization of plant-derived biopharmaceuticals.

Method of highly expressing target protein from plant using RbcS fusion protein and method of preparing composition for oral administration of medical protein using target protein expression plant body

The present invention relates to a method of isolating a protein containing a cellulose binding domain from plants using various structures of cellulose and/or variants thereof. According to the method of isolating a protein, as a high affinity cellulose binding domain is used, a high purity recombinant protein is rapidly and effectively isolated in large quantities at low cost, and thus can be applied in various industrial fields.

Method for separating and purifying protein from plants using cellulose and cellulose binding domain

Growing community of inventors

Pohang-si, South Korea

Yong Jik Lee