Skinmed Co., Ltd.

Sandoz Ag

Amicogen, Inc.

Yong Chul Shin

Won Il Choi

Jin Hwa Kim

Young Sung Yun

Jeung Hoon Lee

Sung Hyun Kim

Zhe Piao

Su-Lim Choi

Yeong Joong Jeon

Youngso Kim

Mi Ran Park

Kyung Hwa Jung

John Y J Jeon

Dae Beom Kwon

So-Young Park

Yang Ho Jo

Youngsoo Kim

John Yj Jeon

Jong Jin Kim

The present disclosure relates to an acetylcholine receptor-binding peptide and, more particularly, to novel peptides which exhibit a wrinkle amelioration effect by binding the peptides to an acetylcholine receptor on which acetylcholine acts, thereby blocking secretion of acetylcholine. Peptides according to the present disclosure suppress secretion of acetylcholine by having a high binding strength with the acetylcholine receptor, thereby strongly binding the peptides to acetylcholine. Therefore, a cosmetic composition and a pharmaceutical composition comprising the peptides according to the present disclosure as an active ingredient exhibit an excellent wrinkle ameliorating effect.

Acetylcholine receptor-binding peptide

The present invention relates to a transdermal nano-carrier and, more specifically, to a nano-carrier having a chitosan-based nano-sponge structure. According to the present invention, as a nano-carrier having enhanced transdermal delivery on the basis of a complex containing chitosan is provided, it is possible to effectively deliver drugs, cosmetic materials, etc. into the skin.

Chitosan-pluronic complex and nano-carrier comprising same

The present invention relates to a mutated immunoglobulin-binding protein having increased alkaline tolerance and, more specifically, to an immunoglobulin-binding protein in which, with respect to the A-domain of Staphylococcal protein A, or a functional variant thereof, an amino acid at a specific site is mutated and thereby exhibits an increased chemical stability at an alkaline pH value in comparison to a parental molecule. The present invention can provide an antibody-purifying immunoglobulin-binding protein ligand and matrix which have enhanced alkaline tolerance and accordingly enhanced stability in multiple times of alkaline cleaning.

Mutated immunoglobulin-binding protein having increased alkaline tolerance

A CPC acylase mutant of the present invention has an improved reactivity and specific activity to CPC, which can be efficiently employed for directly preparing 7-ACA from CPC by a one-step enzymatic method.

Cephalosporin C acylase mutant and method for preparing 7-ACA using same

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Jinju-si, South Korea

Yong Chul Shin