Fudan University

The Florida State University Research Foundation, Inc

Yong Chu

Deyong Ye

Lu Zhou

Yan Chen

Binghe Wang

Chaofeng Dai

Yali Li

Qi Huang

Jintong Yang

Jinyu Fei

Penghui Wang

Haojun Gong

Zhikuan Zhang

Mingguang Mo

Xiangyu Qi

Lifang Wang

Alkoxybenzeno five- or six-member heterocyclic amines compounds, their pharmaceutically acceptable salts, and pharmaceutical compositions are used as the active ingredients, and their application in drugs which can prevent and cure diseases caused by abnormal increasing of SM. These diseases caused by abnormal increasing of SM include atherosclerosis, type II diabetes, fatty liver, obesity, metabolic syndromes, enteritis and other inflammatory diseases.

Alkoxybenzo-five-membered (six-membered) heterocyclic amine compound and pharmaceutical use thereof

2-alkoxy benzene formyl arylamine compounds and their pharmaceutical salts are disclosed. The compounds can act as sphingomyelin synthase (SMS) inhibitors to treat diseases caused by abnormal increasing of sphingomyelin (SM). The pharmaceutically acceptable salts and pharmaceutical compositions of the compounds are used as active ingredients in drugs which can prevent and cure diseases caused by SM level abnormal increase. These diseases include atherosclerosis, fatty liver, obesity, type diabetes, and other metabolic syndromes.

2-alkyloxy benzene formyl arylamine compound and pharmaceutical use thereof

Disclosed are conjugates that can bind to one or more site on cancer cell surface, for example, surface proteins, compound specific receptors and carbohydrates that comprise the surface of specific cell types. The disclosed conjugates can thereby serve as indicators identifying the presence of cancerous tissue.

Cellular recognition conjugates and methods of use for the histological analysis of cancer tissue using MALDI-MS imaging

Growing community of inventors

Shanghai, China

Yong Chu