Sk Chemicals Co., Ltd.

Korea Research Institute of Chemical Technology

Yong-Baik Cho

Keun Ryu

Wie-Jong Kwak

Chang-Kyun Han

Hae In Rhee

Nam Kyu Lee

Jung Bum Yi

Joo Hyon Kim

Hunseung Yoo

In Ho Jung

Nam Ho Kim

Eun Ju Lee

Young-Dae Gong

Je Ho Ryu

Moon-Kook Jeon

Key An Um

Sukho Lee

Jin-Soo Seo

So Yoon Lee

Do Seung Kum

Taek-Soo Kim

Mi-Sook Dong

Ki Won Joung

Jeong-Ran Kim

Kiwon Joung

Hun Seung Yoo

Jae Yoon Jung

Hee Jae Shin

Taek Su Kim

Jung Bum Lee

Hye Yeon Baek

Hyung Ook Kim

Jun Won Lee

Keun Ho Ryu

The present invention relates to an extract isolated from Sophorae Radix useful for prevention and treatment of respiratory diseases. More specifically, the present invention relates to a pharmaceutical drug comprising the Sophorae Radix extract having excellent effects of inhibiting airway contraction, respiratory infections, 5-lipoxygenase activity, phosphodiesterase 4 activity, airway hyper-responsiveness and airway remodeling; antagonistic activity against leukotriene D4; and an antitussive effect, thus being useful for prevention and treatment of respiratory diseases such as asthma, acute or chronic bronchitis, allergic rhinitis, acute upper respiratory infections and acute lower respiratory infections, and the like.

Sophorae Radix extract for prevention and treatment of respiratory diseases

The present invention relates to a herbal drug composition for cartilage protection comprising plant extracts of Clematis Radix, Trichosanthis Radix, and Prunellae Spica and an optimal content of rosmarinic acid to: (i) alleviate pains; (ii) inhibit the acute/chronic inflammation, platelet/whole blood aggregation, immunocyte (B-lymphcyte and T-lymphcyte) proliferation, inflammation-inducing enzyme activities, and enzyme activities associated with degradation of joint tissue; (iii) scavenge activity of toxic active oxygen radicals; and (iv) further provide excellent cartilage protection activity to be effectively used as an anti-inflammatory agent with analgesic effects, blood circulation enhancer, arthritis therapeutic agent and cartilage protective.

Herbal drug composition for cartilage protection

The present invention relates to a novel benzopyran derivative having goodantagonistic activity on TGF-&#x3b2; receptor which can be effectively used as a prophylactic and therapeutic agent for liver disease as well as several fibroplasiadiseases such as hepatic fibrosis, liver cirrhosis, pulmonary fibrosis, dermatosclerosis, glomerular fibrosis and the like; and a pharmaceutical use thereof.

Benzopyran derivatives having inhibitory activities against liver fibrosis and cirrhosis and their pharmaceutical uses

The invention relates to novel pyridine derivatives having an inhibitory effect on production of cytokines, which are involved in inflammatory responses, thus suggesting its usefulness as therapeutic agents for treating diseases related to inflammation, immune, chronic inflammation as well as an agent having an anti-inflammatory and analgesic effect. Further, this invention relates to a method of manufacturing the same and a pharmaceutical composition containing the same.

Pyridine derivatives, a process for their preparation and a pharmaceutical composition containing the same

Disclosed is a method for extracting and purifying active constituents from honeysuckle (Thunb.) and its use. More particularly, this invention relates to an extraction and purification method of active constituents including sweroside from for honeysuckle stem (stem of honeysuckle where leaves are removed) by removing tannins, hardly soluble flavonoids, saponins, and the like. Thus obtained active constituents have better anti-inflammatory and analgesic effect, are safer and more stable than the conventional active constituents obtained from honeysuckle flower or honeysuckle leaves, and include sweroside which is an effective active ingredient of anti-inflammatory and analgesic drug.

[object Object]

Growing community of inventors

Anyang-si, South Korea

Yong-Baik Cho