Ethicon Endo-surgery, Inc.

Yolanda F Carter

John A Hibner

Steven G Hall

Julia Hwang

Frederick E Shelton, IV

Jerome R Morgan

Wells D Haberstich

John B Schulte

Michael D Cronin

Rebecca J Mollere

Patrick D Dugan

Joanne Hull

Julia J Hwang

A treatment system comprises an outer sheath and an end effector. The end effector has a plurality of cutting features, at least a portion of which are configured to debride a tissue surface when the end effector is actuated. The cutting features may also be configured to harvest tissue. A medical fluid reservoir is in fluid communication with the end effector, such that the end effector may deliver a medical fluid to a target site such as a fistula. The medical fluid may include harvested tissue cells and a scaffold material. A vacuum cannula may be positioned coaxially within the interior cavity of the end effector, and an RF probe may be positioned co-axially within the interior cavity of the vacuum cannula. The vacuum cannula and RF probe may be used together to seal a fistula in which medical fluid has been dispensed.

Instrument for debriding fistula and applying therapeutic cells

A tissue treatment device comprises a housing having a chamber that receives a treatment fluid mixture of tissue morsels and a scaffold material. A debriding shaft including a plurality of cutters is coupled with the housing. The debriding shaft extends proximally within the chamber and extends distally from the end of the housing. The debriding shaft is inserted within a treatment site such as a fistula tract and is rotated and reciprocated such that the debriding shaft removes tissue cells along the site. The site is flushed with saline or other irrigating fluid followed by application of the treatment fluid mixture. The chamber of the housing comprises agitators positioned adjacent the debriding shaft. The treatment fluid mixture passes through the chamber of the housing along and between the outer surface of the debriding shaft and the agitators for thorough mixing before exiting the device at the treatment site.

Instrument for debriding tissue and applying therapeutic cells

A surgical stapler includes first and second tissue clamping members and a reservoir configured to hold a tissue treatment composition. The first tissue clamping member is configured to receive a plurality of staples. The second tissue clamping member comprises an anvil configured to form the staples. The reservoir may be provided in a handle portion of the surgical stapler, and a fluid conduit may be used to communicate the tissue treatment composition from the reservoir. An end effector lumen may selectively communicate with the fluid conduit. The lumen may also be in communication with openings to further communicate the tissue treatment composition to tissue or to a scaffold material positioned adjacent to tissue. A reservoir may alternatively be provided in one of the clamping members. A knife member may pierce a housing defining the reservoir, and a resilient member may then urge a tissue treatment composition from the housing.

Methods and apparatus for delivering tissue treatment compositions to stapled tissue

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Union, KY, United States of America

Yolanda F Carter