Lion Corporation

Yoji Yamazaki

Tsuneo Miyahara

Seiji Morishima

Shuji Sasaki

Toshiyuki Okada

An oral composition comprises a nonionic antimicrobial or germicidal agent and at least one amphoteric surface active agent selected from the group consisting of compounds of the following general formulae (1) and (2): ##STR1## wherein R represents an alkyl group having 1 to 18 carbon atoms, and n and m are independently an integer of from 1 to 10. The composition preferably further comprises an alkyl sulfate.

Oral composition

There is provided an oral composition containing a hydroxamic acid represented by the formula R--CH.sub.2 --CO--NHOH (where R is an alkyl group or alkoxyphenyl group) or a salt thereof such as 2-(4-butoxyphenyl)acetohydroxamic acid, 2-(4-methoxyphenyl)acetohydroxamic acid, caprylohydroxamic acid, or laurohydroxamic acid. The oral composition prevents Streptococcus mutans from colonizing in the oral cavity and is effective in preventing dental caries and also in preventing and remedying periodontal disease.

Oral compositions comprising hydroxamic acids and salts thereof

A reagent for the enumeration of oral gram-negative bacteria, such as Bacteriodes melaninogenicus, Capnocytophaga sp. and Eikenelia corrodens, by an indirect fluorescent antibody method is provided which utilizes an unlabelled antiserum to oral gram-negative bacteria and a fluorescent conjugated antibody obtained by immunizing an animal of a different species than the antiserum with .gamma.-globulin of an animal of the same species as the antiserum. A sample containing oral gram-negative bacteria to be enumerated is treated with the antiserum and the reaction product obtained is then treated with the fluorescent conjugated antibody to enumerate the bacteria in the sample by observing under a fluorescent microscope.

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Hiratsuka, Japan

Yoji Yamazaki