Fuji Photo Film Company, Limited

Fujifilm Corporation

Yoichi Nagai

Naoyuki Kawanishi

Shinichi Nakai

Takashi Ando

Shigehisa Sugiyama

Nobuyuki Haraguchi

Koichi Kuno

Hideaki Kagawa

Souichi Kohashi

Toshiki Takei

Provided is a cell culture apparatus including a culture vessel that stores a cell suspension containing cells; a first filter part that has a first filter membrane that performs membrane separation treatment on the cell suspension extracted from the culture vessel; a first circulation flow path that allows components blocked by the first filter membrane to return to the culture vessel; a second filter part that has a second filter membrane that performs membrane separation treatment on components of the cell suspension permeated through the first filter membrane; a second circulation flow path that allows components permeated through the second filter membrane to return to the culture vessel; and a recovery flow path that recovers components blocked by the second filter membrane. In the cell culture apparatus, an average hole diameter of the first filter membrane is 20 μm or smaller, and 0<B/A≤0.5 is satisfied in a case where an average hole diameter of the first filter membrane is A and an average hole diameter of the second filter membrane is B; or an average hole diameter of the first filter membrane is 20 μm or smaller, and the second filter membrane is an ultrafiltration membrane.

Cell culture apparatus and cell culture method

Provided is a cell culture apparatus including a culture vessel that stores a cell suspension containing cells; a first filter part that has a first filter membrane that performs membrane separation treatment on the cell suspension extracted from the culture vessel; a first circulation flow path that allows components blocked by the first filter membrane to return to the culture vessel; a second filter part that has a second filter membrane that performs membrane separation treatment on components of the cell suspension permeated through the first filter membrane; a second circulation flow path that allows components permeated through the second filter membrane to return to the culture vessel; and a recovery flow path that recovers components blocked by the second filter membrane. In the cell culture apparatus, an average hole diameter of the first filter membrane is 20 &#x3bc;m or smaller, and 0&#x3c;B/A&#x2264;0.5 is satisfied in a case where an average hole diameter of the first filter membrane is A and an average hole diameter of the second filter membrane is B; or an average hole diameter of the first filter membrane is 20 &#x3bc;m or smaller, and the second filter membrane is an ultrafiltration membrane.

The present disclosure provides a membrane separation method of a cell suspension which can appropriately separate cells from debris, and a cell culture device. That is, membrane separation processing of the cell suspension is performed using a filtration membrane which includes an inlet-side opening formed on one surface and an outlet-side opening, which is formed on the other surface and communicates with the inlet-side opening, and in which the inlet-side opening and the outlet-side opening are disposed at positions deviated in a direction parallel to the surfaces of the membrane.

Membrane separation method of cell suspension, and cell culture device

Disclosed are a method for preparing grains of silver salt of an organic acid by reacting a solution containing silver ions and a solution containing an alkali metal salt of an organic acid, in which the reaction is performed in sealed mixing means and which comprises steps of supplying the solution containing silver ions into a reaction field solution before introduced into the sealed mixing means, and supplying the solution containing an alkali metal salt of an organic acid into the reaction field solution or sealed mixing means to which the solution containing silver ions has been supplied, etc. According to the present invention, high quality grains of silver salt of an organic acid can be efficiently produced at low cost.

Method and apparatus for preparing grains of silver salt of organic and method for producing thermally processed image recording material

Method and apparatus for preparing grains of silver salt of organic acid and method for producing thermally processed image recording material

A method for producing a silver salt of an organic acid, which comprises steps of reacting (1) a solution containing silver ions in water or in a mixture of an organic solvent and water, with (2) a solution or suspension containing an alkali metal salt of an organic acid in water, in a mixture of an organic solvent and water, or in an organic solvent to prepare a silver salt of an organic acid, and removing a byproduct salt by a desalting operation, wherein a dispersing agent having a molecular weight of 3000 or less is added and dispersed during a time period of from before the reaction to before the desalting operation. There is provided a method for producing a silver salt of an organic acid, which can provides low fog, high sensitivity and high concentration of blackening when it is used for photothermographic materials, and is suitable for the production of photothermographic materials having low haze and less image degradation after storage.

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Kanagawa, Japan

Yoichi Nagai