Teijin Limited

Kyoto University

Keio University

Nippon Paint Automotive Coatings Co., Ltd

Fujimoto Chemicals Co., Ltd.

Yohei Okada

Hideyuki Okano

Kazuhito Kobayashi

Koichi Imamura

Yusuke Nakata

Ryuhei Kanzaki

Shinya Yamanaka

Kazuhiro Chiba

Atsushi Sasaki

Shoichi Maekawa

Masaya Nakamura

Kyoko Miura

Hideaki Umemoto

Takuya Onaka

The present invention relates to an alkoxyphenyl derivative capable of synthesizing an oligonucleotide by a quicker liquid phase synthesis method than in the prior art, a protected nucleoside and a protected nucleotide to which the alkoxyphenyl derivative is bonded, a method for producing an oligonucleotide using the same, and a method for selectively removing the alkoxyphenyl derivative moiety and the like. A compound represented by the general formula (1) or a derivative thereof:

Alkoxyphenyl derivatives, protected nucleosides and protected nucleotides, method for producing oligonucleotides, and method for removing substituents

A polycarbonate resin composition or a copolymer, comprising, as main repeating units, a carbonate unit (a-1) having a fluorene ring in a side chain, a carbonate unit (a-2) represented by the following formula (a-2): (wherein W represents an alkylene group having 1 to 20 carbon atoms or a cycloalkylene group having 6 to 20 carbon atoms, R represents a branched or linear-chain alkyl group having 1 to 20 carbon atoms or a cycloalkyl group having 6 to 20 carbon atoms optionally having a substituent, and u represents an integer of 0 to 3), and a carbonate unit (a-3) derived from 2,2-bis(4-hydroxyphenyl)propane, wherein

Polycarbonate resin composition or copolymer, and optical film

A method for differentiating a human differentiated cell-derived pluripotent stem cell into a neural stem cell is provided, which includes the steps of: making an embryoid body from the human differentiated cell-derived pluripotent stem cell; and culturing the embryoid body in a medium containing LIF to differentiate into a neural stem cell, so that, when the neural stem cell is allowed to differentiate in vitro after multiple subculturing of the neural stem cell, it differentiate mainly into neurons but substantially not into glial cells.

Culture method of embryoid bodies and/or neural stem cells derived from human differentiated cell-derived pluripotent stem cells

To provide a hard coating composition which forms a hard coat layer that has high visibility and good hardness, while having stretchability. To provide a technique which is capable of effectively preventing blocking phenomenon in a layered product such as a resin film without adversely affecting the visibility. The present invention provides a hard coating composition which contains (A) a phenolic novolac acrylate that has two or more acrylate groups and (B) an aromatic group-containing mono or poly(meth)acrylate compound that contains 1-2 mol of an alkylene oxide structure having two or three carbon atoms in each molecule. This hard coating composition contains 60-85 parts by mass of the phenolic novolac acrylate (A) and 15-30 parts by mass of the (meth)acrylate (B) per 100 parts by mass of the resin component contained in the hard coating composition.

Hard coating composition and composition for forming a high refractive index antiblocking layer

The purpose of the present invention is to provide a transparent electroconductive laminate having extremely high visibility. A transparent electroconductive laminate in which a hard coat layer, a color difference adjustment layer, and a transparent electroconductive layer are formed in this order, wherein (1) the hard coat layer being obtained by applying and curing a hard coating composition including (A) a phenol Novolac-type acrylate having two or more acrylate groups and (B) an aromatic-group-containing mono- or poly(meth)acrylate compound having 1-2 moles of a C2 or C3 alkylene oxide structure in the molecule thereof, (2) and the color difference adjustment layer includes a cured resin component (i), and metal oxide particles (ii) having an average primary particle diameter of 100 nm or less and/or metal fluoride particles (iii); having an average primary particle diameter of 100 nm or less, where the total mass of particles (ii) and (iii) in the color difference adjustment layer is 0-200 parts by mass with respect to 100 parts by mass of the cured resin component (i).

Transparent electroconductive laminate

To efficiently identify and select a clone from clones of induced pluripotent stem cells (iPS cell) having low tumor formation rate in vivo when allowed to differentiate and transplanted in a living body, iPS cells of the clones are induced to differentiate, undifferentiated cells among the cells after the induction of differentiation are detected, and a clone having the content of the undifferentiated cell below a control is selected.

Method for selecting clone of induced pluripotent stem cells

Growing community of inventors

Tokyo, Japan

Yohei Okada