Research Foundation Itsuu Laboratory

Yohei Amano

Koichi Shudo

Masayuki Noguchi

A compound represented by the following general formula (I): [wherein Rrepresents hydrogen atom or a Calkyl group, A and B represent &#x2014;(CH)&#x2014;, &#x2014;(CH)&#x2014;or &#x2014;(CH)&#x2014;, X represents &#x2014;N(R)&#x2014;CO&#x2014;(Rrepresents hydrogen atom or a Calkyl group), &#x2014;CO&#x2014;N(R)&#x2014;(Rrepresents hydrogen atom or a Calkyl group), &#x2014;C(R)&#x2550;C(R)&#x2014;(Rand Rrepresent hydrogen atom or a Calkyl group), or &#x2014;N(R)&#x2014;SO&#x2014;(Rrepresents hydrogen atom or a Calkyl group), and Ar represents an aryldiyl group or a heteroaryldiyl group], which has a retinoid action and is useful as an active ingredient of a medicament.

Tricyclic amide compound

A compound represented by the following general formula (I): [wherein Rrepresents hydrogen atom or a Calkyl group, A and B represent &#x2014;(CH)&#x2014;, &#x2014;(CH)&#x2014; or &#x2014;(CH)&#x2014;, X represents &#x2014;N(R)&#x2014; (Rrepresents hydrogen atom or a Calkyl group), &#x2014;CO&#x2014;, &#x2014;C(&#x2550;N&#x2014;R)&#x2014; (Rrepresents hydrogen atom or a Calkyl group), or &#x2014;C(&#x2550;C(R)(R))&#x2014; (Rand Rindependently represent hydrogen atom or a Calkyl group), and Ar represents an aryldiyl group or a heteroaryldiyl group], which has an action of controlling physiological activities of retinoids and useful as an active ingredient of a medicament.

Growing community of inventors

Tokyo, Japan

Yohei Amano