Edwards Lifesciences Corporation

Valcare, Inc.

Yoav Rozen

Boaz Manash

Darshin S Patel

Dinesh L Sirimanne

Khen Perlmutter

Zohar Kiblitski

Tri D Tran

Nadav Yellin

Shuki Porath

Noa Axelrod Manela

Eyal Leiba

Noa Axelrod

Jocelyn Chau

Samuel M Shaolian

Eitan Atias

Guy Rogel

Yuri Falkovich

David Mark Taylor

Alexander J Siegel

Raphael Benary

Ofir Witzman

Aviad Galler

Troy Thronton

Guy Shimel

David Meerkin

Anchoring or docking devices configured to be positioned at a native valve of a human heart and to provide structural support for docking a prosthetic valve therein. The docking devices can have coiled structures that define an inner space in which the prosthetic valve can be held. The docking devices can have enlarged end regions with circular or non-circular shapes, for example, to facilitate implantation of the docking device or to better hold the docking device in position once deployed. The docking devices can be laser-cut tubes with locking wires to assist in better maintaining a shape of the docking device. The docking devices can include various features to promote friction, such as frictional cover layers. Such docking devices can have ends configured to more securely attach the cover layers to cores of the docking devices.

Heart valve docking coils and systems

A docking device for docking a prosthetic valve at a native valve of a heart can include a coil comprising a plurality of turns and having a proximal end and distal end. The docking device can further include a first covering disposed around and covering the coil from the distal end to the proximal end of the coil, and a second covering disposed over the first covering. A distal end and proximal end of the second covering are spaced away from a distal end and proximal end, respectively, of the first covering.

Heart valve docking devices and systems

Systems and methods usable in delivering a docking device to a native valve of a patient's heart. A distal region of a delivery catheter can be positioned in an atrium of the heart and a distal tip can be positioned at or near a commissure of the native valve. The docking device can be located within the delivery catheter. A pusher, such as a pusher wire or tube, of a pusher tool can be advanced distally through the delivery catheter, wherein the pusher can push the docking device along within the delivery catheter. The docking device can be connected to the pusher tool by a line, such as a suture. A member of the pusher tool can be rotatable to change the amount of the suture extending from the pusher tool.

Systems and mechanisms for deploying a docking device for a replacement heart valve

The present disclosure relates to methods and systems for aligning annuloplasty rings during surgical procedures and selectively engaging portions of the targeted annuli. Specifically, the disclosure is directed to methods and systems for aligning an annuloplasty ring or a toroidal portion thereof with natural fiducials present at or near an annular target, and engaging the annulus at the points aligned with the natural fiducials.

Annuli engagement and reshaping using natural fiducials

The present disclosure relates to methods, systems, subsystems, and kits for aligning an annuloplasty ring or a toroidal portion thereof with a natural fiducial in an annular target.

Methods and systems for annuloplasty alignment

Docking devices for docking a prosthetic valve at a native valve of a heart can include a coiled docking anchor and a retrieval suture. The docking device and retrieval suture can be configured for improved retention and retrieval of the docking device after deployment. The docking devices can have an end portion with a central axis. The retrieval suture can be connected to the end portion such that a line of force applied by applying tension to the retrieval suture is substantially aligned with the central axis.

Prosthetic ring valve assemblies are disclosed. A prosthetic valve ring assembly includes an outer tube and a plurality of anchors. The outer tube includes a plurality of windows. The plurality of anchors are positioned inside the outer tube and about a perimeter of the outer tube. The plurality of anchors are configured to be emitted from the plurality of windows in order to anchor the prosthetic valve ring assembly to annulus tissue of a patient.

Mitral or tricuspid repair systems with multi-directional anchors

Disclosed herein are embodiments related to a method for performing a minimally invasive procedure, the method including delivering an annuloplasty ring in a linear shape using a delivery system. In some embodiments, the delivery of the annuloplasty ring may utilize a trans-septal approach or a trans-apical. In some embodiments, the delivery system may position the annuloplasty ring using a flexible stabilizing mechanism and/or activate one or more anchors to extend outward from the annuloplasty ring.

Stabilizing and adjusting tool for controlling a minimally invasive mitral / tricuspid valve repair system

A delivery catheter is in various embodiments configured to deliver an anchoring device to a native valve annulus of a patient's heart, where the anchoring device can better secure a prosthesis at the native annulus. The delivery catheter can includes a distal section that includes one or more spines or is laser cut to assume a particular shape for better facilitating delivery of the anchoring device at the implant site and can include a flexible tube, a first pull wire, and a second pull wire. The flexible tube can comprise a bore extending between the first end and the second end sized for passing the anchoring device therethrough. The distal portion can comprise a first flexing section and a second flexing section. Actuation of the first pull wire and the second pull wire can cause the flexible tube to move from a first configuration to a second configuration.

Growing community of inventors

Binyamina, Israel

Yoav Rozen