Advanced Cardiovascular Systems, Inc.

Abbott Cardiovascular Systems, Inc.

Other

Yiwen Tang

Stephen D Pacetti

Syed F A Hossainy

Lothar W Kleiner

Syed Faiyaz Ahmed Hossainy

Thierry Glauser

Andrew C Tung

Eugene T Michal

Mikael Trollsas

Gina Zhang

Ni Ding

Fuh-Wei Tang

Jessica R DesNoyer

Qing Lin

Shaw Ling Hsu

Michael H Ngo

Charles David Claude

Manish Gada

Irina Astafieva

Connie S Kwok

Ashok A Shah

John Whatley

Syed Faiyaz Shmed Hossainy

Homayon Askaryar

Wouter Erik Roorda

John Joseph Stankus

Paul M Consigny

Yung-Ming Chen

Florencia Lim

Santosh V Prabhu

Sean A McNiven

Deborah L Kilpatrick

Gordon S Stewart

Jeffrey T Ellis

Bozena Zofia Maslanka

Jessica Reneé DesNoyer

Gene Park

Nam D Pham

Andrew F McNiven

Syed Fa Hossainy

Jessica Renee DesNoyer

Harshad Borgaonkor

Brandon J Yoe

Lothar Walter Kleiner

Michael Huy Ngo

Syed FA Hossainy

Bozena Sofia Maslanka

Jessica Desnoyer

The present disclosure teaches methods of controlling the release rate of agents from a polymeric matrix. The methods relate to the application of pressure, and optionally, in combination with heat, to a polymeric coating.

Methods of treatment of polymeric coatings for control of agent release rates

The present invention provides a semi-crystalline polymer for a coating on an implantable device for controlling release of drug and methods of making and using the same.

Bioabsorbable semi-crystalline polymer for controlling release of drug from a coating

A biocompatible plasticizer useful for forming a coating composition with a biocompatible polymer is provided. The coating composition may also include a biobeneficial polymer and/or a bioactive agent. The coating composition can form a coating on an implantable device. The implantable device can be used to treat or prevent a disorder such as atherosclerosis, thrombosis, restenosis, hemorrhage, vascular dissection or perforation, vascular aneurysm, vulnerable plaque, chronic total occlusion, claudication, anastomotic proliferation for vein and artificial grafts, bile duct obstruction, ureter obstruction, tumor obstruction, or combinations thereof.

Plasticizers for coating compositions

Coatings for an implantable medical device and a method of fabricating thereof are disclosed, the coatings comprising polymers of lactic acid.

Coatings for implantable devices comprising polymers of lactic acid and methods for fabricating the same

A coating for implantable medical devices and a method for fabricating thereof are disclosed. The coating includes a mixture of a hydrophobic polymer and a polymeric hydrophilic additive, wherein the hydrophobic polymer and the hydrophilic additive form a physically entangled or interpenetrating system.

Methods for forming stent coatings comprising hydrophilic additives

Coatings for an implantable medical device and a method of fabricating the coatings are disclosed. The coatings comprise a fluorinated polymer and a biologically beneficial polymer, an example of which includes poly(ethylene-glycol)-block poly(butylene terephthalate)-block poly(ethylene-glycol). A biologically active agent can be additionally conjugated to the biologically beneficial polymer.

Biologically beneficial coatings for implantable devices containing fluorinated polymers and methods for fabricating the same

A copolymer comprising a block of an elastin pentapeptide and method of making and using the copolymer are provided. The copolymer may be used as a coating on a stent. Methods of using a stent coated with the copolymer are also provided.

Depot stent comprising an elastin-based copolymer

Provided herein is a coating an elastic primer layer and the method of making and using the same.

Coatings having an elastic primer layer

The present invention relates to implantable medical devices coated with polymer having tunable hydrophobicity and their use in the treatment of vascular diseases.

Bioabsorbable coating with tunable hydrophobicity

A medical article is disclosed, comprising a biologically degradable AB block copolymer and a biologically degradable polymer that is capable, at equilibrium and at room temperature, of absorbing less than about 5 mass % water.

Biologically degradable compositions for medical applications

A copolymer comprising a block of an elastin pentapeptide and method of making and using the copolymer are provided.

Copolymer comprising elastin pentapeptide block and hydrophilic block, and medical device and method of treating

Methods for making coatings on an implantable device, such as a drug-eluting stent. The coatings comprise a polymer and a drug in a crystalline or partially crystalline form. In addition, implantable devices produced by the methods and methods of using the coated implantable devices are described.

Methods of forming coatings with a crystalline or partially crystalline drug for implantable medical devices

Stent coatings comprising hydrophilic additives

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San Jose, CA, United States of America

Yiwen Tang