Navix International Limited

Biosense Webster (Israel) Ltd.

Biosense, Inc.

Biosense Webster, Inc.

Other

Krimsky, William Sanford

Shalgi, Avi

Waldstreicher, Jonathan Reuben

Bar-Tal, Meir

Hayam, Gal

Schwartz, Yitzhack

Itah, Refael

Amit, Matityahu

Yitzhack Schwartz

Assaf Govari

Yizhaq Shmayahu

Yaara Yarden

Leonid Gluhovsky

Andres Claudio Altmann

Yehonatan Ben David

Yaron Ephrath

Vadim Gliner

Christopher Thomas Beeckler

Shlomo Ben-Haim

Eli Dichterman

Zalman Ibragimov

Asaf Merschon

Meir Bar-Tal

Simon Richard Daniel

Uri Yaron

Mati Amit

Zubin Rustom Wadia

Timothy W Coleman

Joshua Porath

Haim Rodriguez

Justyna Zander

Adi Rabinovich

Marcia Leatham

Natan Sharon Katz

William Sanford Krimsky

Yaron Keidar

Gal Hayam

Michael Levin

Robert D Ainsworth

Assaf Preiss

Jonathan Reuben Waldstreicher

Matityahu Amit

Avi Shalgi

Joel Zilberstein

Refael Itah

Louis J Capezzuto

Shlomo Ben-haim

Meir Bar-tal

Model Dmitri

William Sanford Krimskiy

Rafael Itah

A disaster response system includes a communication infrastructure including a plurality of sensor assemblies configured to generate data indicative of at least one of environmental conditions, motion, position, chemical detection, and medical information; and wirelessly provide the generated data to the communication infrastructure. The system also includes an incident command infrastructure configured to exchange data with the communication infrastructure; and detect an incident based on the data from the sensor assemblies. The system also includes an unmanned aerial vehicle (UAV) configured to deliver a payload in response to the detected incident.

Systems, methods and devices for the rapid assessment and deployment of appropriate modular aid solutions in response to disasters

In some embodiments, a body cavity shape of a subject is reconstructed based on intrabody measurements of voltages by an intrabody probe (for example, a catheter probe) moving within a plurality of differently-oriented electromagnetic fields crossing the body cavity. In some embodiments, the method uses distances between electrodes as a spatially calibrated ruler. Positions of measurements made with the intrabody probe in different positions are optionally related by using spatial coherence of the measured electromagnetic fields as a constraint. Optionally, reconstruction is performed without using a detailed reference (image or simulation) describing the body cavity shape. Optionally, reconstruction uses further information to refine and/or constrain the reconstruction; for example: images, simulations, additional electromagnetic fields, and/or measurements characteristic of body cavity landmarks. Optionally, reconstruction accounts for time-dependent cavity shape changes, for example, phasic changes (e.g., heartbeat and/or respiration), and/or changes in states such as subject hydration, edema, and/or heart rate.

Systems and methods for reconstruction of intra-body electrical readings to anatomical structure

Devices and methods for assessing tissue contact based on dielectric properties and/or impedance sensing are disclosed. In some embodiments, one or more probing frequencies are delivered via electrodes including an electrode in proximity to a tissue (for example, myocardial tissue). In some embodiments, dielectric parameter values, optionally together with other known and/or estimated tissue characteristics, are measured to determine a contact quality with the tissue. In some embodiments, dielectric contact quality is used, for example, in guiding the formation of a lesion (for example, RF ablation of heart tissue to alter electrical transmission characteristics).

Contact quality assessment by dielectric property analysis

Devices and methods for tissue lesion assessment and/or creation based on dielectric properties are disclosed. In some embodiments, one or more probing frequencies are delivered via electrodes including an electrode in proximity to a tissue (for example, myocardial tissue). Measured dielectric properties (such as impedance properties), optionally together with other known and/or estimated tissue characteristics, are used to determine the lesion state of the tissue. In some embodiments, a developing lesion state is monitored during treatment formation of a lesion (for example, ablation of heart tissue to alter electrical transmission characteristics).

Lesion assessment by dielectric property analysis

Methods for creation and use (e.g., for navigation) of displays of flattened (e.g., curvature-straightened) 3-D reconstructions of tissue surfaces, optionally including reconstructions of the interior surfaces of hollow organs. In some embodiments, data comprising a 3-D representation of a tissue surface (for example an interior heart chamber surface) are subject to a geometrical transformation allowing the tissue surface to be presented substantially within a single view of a flattened reconstruction. In some embodiments, a catheter probe in use near the tissue surface is shown in positions that correspond to positions in 3-D space sufficiently to permit navigation; e.g., the probe is shown in flattened reconstruction views nearby view regions corresponding to regions it actually approaches. In some embodiments, automatic and/or easily triggered manual view switching between flattened reconstruction and source reconstruction views is implemented.

Flattened view for intra-lumenal navigation

There is provided a method of displaying a pre-acquired three dimensional (3D) image of at least a portion of an organ of a patient, the method comprising: receiving a plurality of electrical readings, each from a different electrode mounted on a catheter inside the portion of the organ of the patient, wherein the electrodes are mounted on the catheter at known distances from each other, transforming the plurality of electrical readings to a corresponding plurality of image points using a mapping transformation that transforms each electrical reading of the catheter from inside the portion of the organ of the patient to an anatomically corresponding image point in the 3D image based on the known distances, and displaying the 3D image with a marking of at least one of the plurality of image points.

Systems and methods for registration of intra-body electrical readings with a pre-acquired three dimensional image

Methods and systems for position determination of an intrabody probe, targets of an intrabody probe, and or actions to be performed using an intrabody probe are described. In some embodiments, an anatomy being navigated and/or mapped is described by a rule-based schema relating different anatomically identified structures to one another according to their ability to help identify and/or locate one another. Additionally, in some embodiments, data recorded from the intrabody probe is processed according to schema rules in order to provide anatomical identification of the anatomical region which the intrabody probe is sampling, optionally without performing detailed mapping, and/or prior to the availability of detailed mapping of anatomical geometry.

Property- and position-based catheter probe target identification

Systems and methods are described for planning of catheter ablation procedures, and in particular for planning of the placement of lesions and/or parameters used in ablation. In some embodiments, planning is based on thermal and/or dielectric simulation of lesions, individualized to the anatomy of the particular patient. Optionally, a plan comprises planning of a path along which an ablation lesion is to be formed, the ablation lesion optionally comprising one or more sub-lesions. The plan is optionally optimized for one or more criteria including, for example: minimization of path length, minimization of sub-lesion number, simplification of catheter maneuvering, avoidance of collateral damage to non-target tissue, access to the target dependent on anatomy shape and/or catheter mechanics, and/or features of the target anatomy such as tissue wall thickness and/or fiber direction.

Calculation of an ablation plan

In some embodiments, data sensed and/or operational parameters used during a catheterization procedure are used in the motion frame-rate updating and visual rendering of a simulated organ geometry. The organ geometry is rendered as a virtual material using a software environment (preferably a graphical game engine) which applies simulated optical laws to material appearance parameters affecting the virtual material's visual appearance, as part of simulating a scene comprising the simulated organ geometry, and optionally also comprising simulated views of a catheter probe used for sensing and/or treatment. Optionally, measurements of and/or effects on tissue by sensing and/or commanded probe-tissue interactions are converted into material appearance changes, allowing dynamic visual simulation of intra-body states and/or events based on optionally non-visual input data. In some embodiments, physiology, motion physics, and/or other physical processes are simulated based on live inputs as part of associating material appearance properties to the simulated tissue's geometry.

Real-time display of treatment-related tissue changes using virtual material

Methods for estimating of the effectiveness of catheter ablation procedures to form lesions, and particular lesions which together form an ablation segment of an ablation line. Lesion effectiveness parameters are received, and effectiveness, optionally the joint effectiveness, of corresponding ablations (optionally planned, current, and/or already performed) is estimated. In some embodiments, estimating is based on use by computer circuitry of an estimator constructed based on observed associations between previously analyzed lesion effectiveness parameters, and observed lesion effectiveness. Additionally or alternatively, estimators may be constructed based on analytic functions. The estimator is used by application to the received lesion effectiveness parameters.

Estimation of effectiveness of ablation adjacency

Display screen or portion thereof with icon

Disclosed herein is a method of graphically presenting an indicating marker over a 3-D model of a tissue surface during a catheterization procedure, comprising determining a region over the 3-D model, deforming the indicating marker to congruently match a shape defined by the 3-D model across the region at a plurality of positions; and rendering the 3-D model into an image including the deformed indicating marker by generating an image of the 3-D model covered by said deformed indicating marker.

Tissue model dynamic visual rendering

Methods for estimating of the effectiveness of catheter ablation procedures to form lesions. Lesion effectiveness parameters are received, and effectiveness of a corresponding ablation (optionally planned, current, and/or already performed) is estimated. The estimating is based on use by computer circuitry of an estimator constructed based on observed associations between previously analyzed lesion effectiveness parameters, and observed lesion effectiveness. The estimator is used by application to the received lesion effectiveness parameters.

Estimators for ablation effectiveness

Growing community of inventors

Haifa, Israel

Yitzhack Schwartz