Nanjing Sanhome Pharmaceutical Co., Ltd.

Yiping Gao

Yong Wang

Di Zhang

Liwen Zhao

Cang Zhang

Hongyan Chen

Sheng Bi

Yang Nan

Xian Zhang

Yang Liu

Feng Wu

Dezhong Wang

Yuxiu Li

Hongbin Chen

A novel nucleoside phosphoramidate compound of the formula below, or a stereoisomer, salt, hydrate, solvate or crystal thereof for the treatment of Flaviviridae family viral infection, especially hepatitis C viral infection, and having a good anti-HCV effect; a pharmaceutical composition having the compound, or a stereoisomer, salt, hydrate, solvate or crystal thereof: 

Nucleoside phosphoramidate compound and use thereof

In the field of pharmaceutical chemistry compounds of general formula I having heteroaryl alkynyl moiety or pharmaceutically acceptable salts, isomers, solvates, crystals or prodrugs thereof, and pharmaceutical compositions including these compounds, as well as uses of these compounds and compositions thereof in the manufacture of a medicament. The compounds have a strong inhibitory effect on BCR-ABL tyrosine kinase and are useful for treating diseases, such as tumors. 

Heteroaryl alkyne compound and use thereof

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Nanjing, China

Yiping Gao