Incyte Corporation

Yingrui Dai

Jiacheng Zhou

Zhongjiang Jia

Yongzhong Wu

Yongchun Pan

Shili Chen

Jianji Wang

James M Parks

Aibin Zhang

Anthony J Tomaine

The present application provides processes for preparing 4-[3-(cyanomethyl)-3-(3',5&#x2032;-dimethyl-1H, 1&#x2032;H-4,4&#x2032;-bipyrazol-1-yl)azetidin-1-yl]-2,5-difluoro-N-[(1S)-2,2,2-trifluoro-1-methylethyl]benzamide, and phosphoric acid salt thereof, which is useful as a selective (Janus kinase 1) JAK1 inhibitor, as well as salt forms and intermediates related thereto.

Processes of preparing a JAK1 inhibitor

This invention relates to processes for preparing a JAK1 inhibitor having Formula Ia: as well as new forms of the inhibitor.

Processes of preparing a JAK1 inhibitor and new forms thereto

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Wilmington, DE, United States of America

Yingrui Dai