Globeimmune, Inc.

Yingnian Lu

Alex Franzusoff

Thomas H King

Donald Bellgrau

Zhimin Guo

David Apelian

Richard C Duke

Aurelia Haller

Claire Coeshott

Victoria Kelley Hodson

Disclosed are fusion proteins, recombinant nucleic acid molecules, and therapeutic compositions, including yeast-based immunotherapy compositions, for use in the diagnosis, prevention and treatment of adenovirus-36 (Ad-36) infection and sequela thereof.

Compositions and methods for the treatment or prevention of human adenovirus-36 infection

Disclosed are newly discovered Ras mutations and combinations of mutations, proteins and peptides and fusion proteins containing these mutations, nucleic acid molecules encoding such proteins, peptides, and fusion proteins, and a variety of tools and diagnostic, therapeutic, and screening methods associated with the use of such mutations.

Ras mutation and compositions and methods related thereto

The invention provided herein relates to vaccines that can be tailored to achieve a desired immune response. Some compositions provided herein are used for preferentially eliciting a humoral immune response while other compositions are useful for preferentially eliciting a cell-mediated response. Combinations of vaccine compositions are also useful for eliciting both types of responses and/or for modulating the type of immune response elicited. The invention also provides methods for eliciting an immune response in an individual by administering the compositions disclosed herein. These immune responses are useful for protecting an individual from various types of diseases, infections, and undesirable conditions.

Yeast-based vaccine for inducing an immune response

Growing community of inventors

Denver, CO, United States of America

Yingnian Lu