Stc.unm

University of Florida Research Foundation, Incorporated

United States of America As Represented by the Administrator of Nasa

Unm Rainforest Innovations

Ying Wang

David G Whitten

Eric H Hill

Kirk S Schanze

Linnea K Ista

Thomas S Corbitt

Anand Parthasarathy

Eunkyung Ji

Dimitri Dascier

Motokatsu Ogawa

Harry Craig Pappas

Kiran Bhaskar

Yue Zhang

Eva Yung Hua Chi

Arjun Thapa

Patrick L Donabedian

Zhijun Zhou

Yanli Tang

Lina Cui

Anup Sharma

Joseph Grant

Jun Liu

Xiaowei Ma

Philip Deenik

Various embodiments relate to p-phenylene ethynylene compounds as bioactive and detection agents. In various embodiments, the present invention provides a method of inducing germination of microbial spores including contacting the microbial spores with a p-phenylene ethynylene compound. In various embodiments, the present invention provides a method for detecting an enzyme, a method of protein analysis, or a method of detecting a chemical agent, including introducing a p-phenylene ethylylene compound to a composition including an enzyme substrate, and analyzing the fluorescence of the p-phenylene ethynylene compound. Various embodiments provide sensors that include a p-phenylene ethynylene compound and an enzyme substrate.

P-phenylene ethynylene compounds as bioactive and detection agents

A probe comprising a biomarker-triggered moiety, a near infrared (NIR) fluorophore reporter, a self-immolative linker and a self-immobilizing moiety for visualization of senescent cells and methods of use thereof.

Near infrared small molecule probes for the detection of cellular senescence

The present disclosure provides novel poly(phenylene ethynylene) (PPE) compounds, methods for synthesizing these compounds, and materials and substances incorporating these compounds. The various PPEs show antibacterial, antiviral and antifungal activity.

Structure, synthesis, and applications for poly (phenylene) ethynylenes (PPEs)

Various embodiments relate to p-phenylene ethynylene compounds as bioactive and detection agents. In various embodiments, the present invention provides a method of inducing germination of microbial spores including contacting the microbial spores with a p-phenylene ethynylene compound. In various embodiments, the present invention provides a method for detecting an enzyme, a method of protein analysis, or a method of detecting a chemical agent, including introducing a p-phenylene ethynylene compound to a composition including an enzyme substrate, and analyzing the fluorescence of the p-phenylene ethynylene compound. Various embodiments provide sensors that include a p-phenylene ethynylene compound and an enzyme substrate.

The present disclosure provides novel oligo phenylene ethynylene (OPE) compounds, methods for synthesizing these compounds, and materials and substances incorporating these compounds. The various OPEs show antibacterial, antiviral and antifungal activity.

Structure, synthesis, and applications for oligo phenylene ethynylenes (OPEs)

An apparatus and method for forming a Bragg grating on an optical fiber using a phase mask to diffract a beam of coherent energy and a lens combined with a pair of mirrors to produce two symmetrical virtual point sources of coherent energy in the plane of the optical fiber. The two virtual light sources produce an interference pattern along the optical fiber. In a further embodiment, the period of the pattern and therefore the Bragg wavelength grating applied to the fiber is varied with the position of the optical fiber relative the lens.

Fabrication of fiber optic grating apparatus and method

Growing community of inventors

Albuquerque, NM, United States of America

Ying Wang