X-Chem, Inc.

Other

Emc IP Holding Company LLC

X-Rx, Inc.

Vce IP Holding Company LLC

Ying Victor Zhang

Anthony Dominic Keefe

Matthew Clark

Richard W Wagner

John William Cuozzo

Ce Wang

Haihong Ni

Mark J Mulvihill

Lee Babiss

Heather Thomson

Louis Renzetti

Frank Ruebsam

Zhifeng Xie

Diana Gikunju

Rajesh Nandyalam

Paolo A Centrella

Alexander Litovchick

Christopher D Hupp

Christoph Dumelin

Methods, systems, and computer readable mediums for optimizing data processing are disclosed. According to one exemplary embodiment, a method for optimizing data processing includes receiving data usage information associated with at least one user-defined key performance indicator (KPI), determining, using the data usage information, optimization information for optimizing data processing, and providing the optimization information to at least one resource.

Methods, systems, and computer readable mediums for optimizing data processing

The present invention relates to oligonucleotide-encoded libraries and methods of tagging such libraries. In particular, the methods and oligonucleotides can include one or more 2'-substituted nucleotides, such as 2&#x2032;-O-methyl or 2&#x2032;-fluoro nucleotides, and other conditions or reagents to enhance enzyme ligation or one or more chemical functionalities to support chemical ligation.

Methods for tagging DNA-encoded libraries

Methods, systems, and computer readable mediums for sharing user activity data are disclosed. According to one example, a method includes receiving a collection of user activity records, wherein each of the user activity records is associated with at least one user-defined system management query and analyzing the collection of user activity records to identify one or more correlations existing among the user-defined system management queries. The method further includes generating system management compilation data based on the identified one or more correlations and distributing the system management compilation data to a plurality of subscriber entities.

Methods, systems, and computer readable mediums for sharing user activity data

A probabilistic classifying system for a distributed computing environment includes a computer-executable system for obtaining multiple measured values associated with the operation of a plurality of resources of a distributed computing environment. The system uses the measured values to generate a health metric assessment using a probabilistic classifier in which the health metric assessment comprising one of multiple finite health metric assessments. The probabilistic classifier generates the health metric assessment according to the obtained measured values and a statistical inference upon at least a portion of a plurality of previously obtained measured values of the resources of the distributed computing environment.

Probabilistic classifying system and method for a distributed computing environment

The present invention relates to compounds according to Formula I and pharmaceutically acceptable salts, synthesis, intermediates, formulations, and methods of disease treatment therewith, including cancer, lymphocyte homing, chronic inflammation, neuropathic pain, fibrotic diseases, thrombosis, and cholestatic pruritus, mediated at least in part by ATX. 

Substituted spirocyclic inhibitors of autotaxin

Aspects of the present disclosure involve converged infrastructures, and more particularly, systems that automatically select an application programming interface for use in connecting one or more components of the converged infrastructure with management software. Component information is obtained for a particular component within the converged infrastructure. The component information is used in conjunction with various selection metrics to identify an applicable application programming interface.

Dynamic and adaptive programmatic interface selection (DAPIS)

The present invention features compounds having soluble epoxide hydrolase inhibitory activity. The compounds of the invention, alone or in combination with other pharmaceutically active agents, can be used for treating or preventing various medical conditions, such as cardiovascular diseases, respiratory diseases, inflammation, and diabetes.

Soluble epoxide hydrolase inhibitors and uses thereof

The present invention relates to compounds according to Formula 1 and pharmaceutically acceptable salts, synthesis, intermediates, formulations, and methods of disease treatment therewith, including cancer, lymphocyte homing, chronic inflammation, neuropathic pain, fibrotic diseases, thrombosis, and cholestatic pruritus, mediated at least in part by ATX. 

The present invention features benzhydrol-pyrazole derivatives and related compounds having kinase inhibitory activity. The compounds of the invention, alone or in combination with other pharmaceutically active agents, can be used for treating or preventing various medical conditions, such as cancers, inflammatory disorders, or autoimmune disorders.

Benzhydrol-pyrazole derivatives having kinase inhibitory activity and uses thereof

The present invention features tryptoline derivatives and related compounds having kinase inhibitory activity. The compounds of the invention, alone or in combination with other pharmaceutically active agents, can be used for treating or preventing various medical conditions, such as cancers, inflammatory disorders, or autoimmune disorders.

Growing community of inventors

Plano, TX, United States of America

Ying Victor Zhang