At&t Intellectual Property I, L.p.

Genentech, Inc.

Other

University of Texas System

At+t Corp.

Splendorstream, LLC

Washington University

Yale University

Denali Therapeutics Inc.

Adimab, LLC

Yin Sheng Zhang

Mark S Dennis

Kadangode K Ramakrishnan

Divesh Srivastava

Ryan Jefferson Watts

Zihui Ge

Subhabrata Bapi Sen

Michael Rabinovich

Jia Wang

Lili Qiu

Tae Won Cho

Nicholas G Duffield

Jennifer Yates

Ajay Mahimkar

Joy Yu Zuchero

Gregory Alan Lazar

Aman M Shaikh

James A Ernst

Jasvinder Atwal

Matthew Roughan

Jessica Couch

Carsten Lund

William Christopher Fenner

Joanne Emmons

Albert Gordon Greenberg

Sumeet Singh

Susan D Spencer

Adam P Silverman

Suzanna J Scales

John Gregory Klincewicz

David Michael Holtzman

Hong Jiang

Yang Richard Yang

Kartikeya Chandrayana

Thu Nga Bien-Ly

Jing Guo

Andrea Basso

Yan Wu

Balachander Krishnamurthy

Zhuoqing Morley Mao

Michael Feldhaus

Eric Krauland

Cheng Ee

Cecilia Pui Chi Chiu

James Wolter Ernst

Han Hee Song

Yichin Liu

Min-Hsuan Chen

Rinkan Shukla

Yunhua Joy Yu

M Rabinovich

Yunhua Yu Zuchero

Yan Chen

Chunlei Zhang

Fan Liao

Jennifer A Getz

The present disclosure encompasses compositions and methods for effectively treating at least one symptom or sign of Aß plaque or cerebral amyloid angiopathy (CAA) associated symptoms, or for decreasing amyloid plaque load or CAA load. The method comprises administering an effective amount of an anti-ApoE antibody to a mammalian subject, such as to a human.

Anti-ApoE antibodies

In one aspect, antibodies that specifically bind to a human BACE1 protein are provided herein. In some embodiments, the antibodies contain modifications that reduce effector function, extend serum stability or serum half-life, or promote heterodimerization. In other aspects, bispecific antibodies and pharmaceutical compositions comprising antibodies that bind to human BACE1 protein are provided herein. Methods for inhibiting amyloid-&#x3b2; formation and/or aggregation, inhibiting amyloid plaque formation, and treating neurodegenerative diseases are also provided herein.

Anti-BACE1 antibodies and methods of use thereof

The application introduces the technology of Internet of Things into field of attire design, and creates a communicative and sensitive device: the composite and convertible attire with network communication and intelligent sensitive features, referred to as COMS Attire, its purpose is to liberate mobile devices from 'hand-held' mode, and use the convertibility of attire to protect and enhance intelligent elements. Attire is big in size, large in capacity, deformable in shape, attachable and detachable in structure, and its carried items can be exposed and concealed at will. Attire is a daily necessity in people's lives, and the most suitable place for development of new generation of mobile intelligent device to replace the miniaturized traditional mobile one; the technical achievements of hardware 'miniaturization' make COMS attire more intelligent, more fashionable and popular with users. COMS attire increases the choice of chip types, and expands the installation space of intelligent components.

Convertible combination of attire and backpack with network communication and intelligent sensing features

The present disclosure encompasses compositions and methods for effectively treating at least one symptom or sign of A plaque or cerebral amyloid angiopathy (CAA) associated symptoms, or for decreasing amyloid plaque load or CAA load. The method comprises administering an effective amount of an anti-ApoE antibody to a mammalian subject, such as to a human.

The present invention relates to anti-transferrin receptor antibodies and methods of their use.

Anti-transferrin receptor antibodies and methods of use

The present invention relates to bispecific antibodies that bind to transferrin receptor and BACE1 and methods of using the same.

Anti-transferrin receptor / anti-BACE1 multispecific antibodies and methods of use

The present invention relates to antibodies that bind blood brain barrier receptors (BBB-R) and methods of using the same.

Low affinity blood brain barrier receptor antibodies and uses thereof

A system and method identify a network upgrade from a data set including a plurality of configuration sessions. The system performs the method by receiving a plurality of configuration sessions. Each of the configuration sessions comprises a plurality of configuration commands. The configuration commands are generated by a same user identifier and within a time threshold. The method further includes identifying one of the configuration sessions as a network upgrade session. The identification is based on a rareness of the configuration session or a skewness of the configuration session.

Method and system for detecting network upgrades

Recommendation systems are widely used in Internet applications. In current recommendation systems, users only play a passive role and have limited control over the recommendation generation process. As a result, there is often considerable mismatch between the recommendations made by these systems and the actual user interests, which are fine-grained and constantly evolving. With a user-powered distributed recommendation architecture, individual users can flexibly define fine-grained communities of interest in a declarative fashion and obtain recommendations accurately tailored to their interests by aggregating opinions of users in such communities. By combining a progressive sampling technique with data perturbation methods, the recommendation system is both scalable and privacy-preserving.

User-powered recommendation system

The invention provides anti-mesothelin antibodies and immunoconjugates and methods of using the same.

Anti-mesothelin antibodies and immunoconjugates

A method, system and computer program product for reducing network delay in video conferencing using random tree pushing. A plurality of nodes is randomly selected as next hop forwarders for a piece of content by a source who generates a video stream. Additional next hop forwarders are added to the randomly selected plurality of nodes to form a set of next hop forwarders until a total upload bandwidth of all next hop forwarders is no less than a bandwidth required to deliver the video stream to a set of receivers. The set of receivers in a video session is partitioned and each of the set of receivers is assigned to one of the set of next hop forwarders for forwarding the video stream to an assigned receiver either directly or through a multi-hop path.

Efficiently distributing video content using a combination of a peer-to-peer network and a content distribution network

A method for disseminating content over an overlay network having a plurality of routers in communication with providers and consumers of content is disclosed. A router in the overlay network receives a content descriptor corresponding to a query for content from a node, and generates a subscriber interface list based on the query for the content. The subscriber interface list is transmitted to a plurality of subsequent routers in the overlay network, wherein a content identified by the subsequent routers that correspond to the query will be routed to the router based on the subscriber interface list. The router receives first and second documents corresponding to the query for the content from the node. If the second document is the duplicate, the router deletes the second document and transmits the first document to the node or if not the router transmits both the first and second documents to the node.

Methods and systems for content access and distribution

Growing community of inventors

Richmond, CA, United States of America

Yin Sheng Zhang