Other

Cspc Zhongqi Pharmaceutical Technology (shijiazhuang) Co., Ltd.

Wuxi Life Fountain Biotech Co., Ltd

Cspc Zhongqi Pharmaceuticall Technology (shijiazhuang) Co., Ltd.

Cspc Zhongqi Pharmaceutical Technology Co., Ltd.

Yikai Wang

Shuhui Chen

Jian Li

Zhengxia Chen

Jie Li

Guoping Hu

Tao Feng

Meibi Dai

Linlin Chen

Xing Liu

Xiaoxin Chen

Chaofeng Long

Zhuowei Liu

Zhen Gong

Jikui Sun

Haixia Zhao

Yangyang Xu

Qiu Li

Rongxin Huang

Deyao Li

A series of pyrazolopymidine derivatives, and use thereof in the preparation of a medicament for treating disease associated with FGFR and c-Met. The pyrazolopymidine derivative is a compound represented by formula (I), a tautomer, or a pharmaceutically acceptable salt thereof.

Azaindole derivative and use thereof as FGFR and C-Met inhibitor

Provided is a FGFR inhibitor, designating a compound represented by formula (I) or a pharmaceutically acceptable salt thereof. Also provided is the application of a drug for treating solid tumors, such as FGFR related diseases. 

Substituted pyrrolo[2,1-f][1,2,4]triazines as FGFR inhibitors

Disclosed are an FGFR inhibitor and the use thereof in the preparation of a drug for treating FGFR-related diseases. In particular, disclosed are a compound as shown in formula (I) and a pharmaceutically acceptable salt thereof. 

Provided are a class of compounds as shown in formula (I) as FGFR4 inhibitors, and pharmaceutically acceptable salts thereof, preparation methods therefor and the use thereof in the preparation of drugs for treating FGFR4-related diseases. 

FGFR4 inhibitor and preparation method and use thereof

Growing community of inventors

Shanghai, China

Yikai Wang