Jiangsu Hengrui Medicine Company Ltd.

Shanghai Hengrui Pharmaceutical Co., Ltd.

Yifang Wang

Weikang Tao

Hua Ying

Hu Ge

Jinping Shi

Qiyue Hu

Tingting Li

Guimei Yang

Lianshan Zhang

Ling L Zhang

Zhen Zhang

Yayuan Fu

Dongbing Cui

Jiajian Liu

Ling Zhang

Haoying Zhang

Disclosed are an antibody capable of binding to thymic stromal lymphopoietin and the use thereof. Disclosed are an anti-TSLP antibody, comprising a murine antibody, chimeric antibody and humanized antibody of the light chain and heavy chain variable regions of the anti-TSLP antibody and antigen-binding fragments thereof, or a pharmaceutically acceptable salt or solvent compound thereof, and the use thereof as a medicament for treating asthma, especially the use thereof in the preparation of a drug for treating TSLP-positive diseases or conditions.

Antibody capable of binding to thymic stromal lymphopoietin and use thereof

Provided are an IL-5 antibody, an antigen binding fragment thereof, and a medical application therefor. The present invention comprises a mouse-derived antibody containing an IL-5 antibody CDR region, a chimeric antibody, a humanized antibody, and a pharmaceutical composition comprising said IL-5 antibody and said antigen binding fragment thereof, as well as the use of the pharmaceutical composition as a drug.

IL-5 antibody, antigen binding fragment thereof, and medical application therefor

Provided is a humanized antibody and chimeric antibody that specifically binds human sclerostin. The antibodies can be used for treating human bone metabolism related diseases such as osteoporosis (OP).

Anti-sclerostin antibody, antigen binding fragment and medical use thereof

Growing community of inventors

Shanghai, China

Yifang Wang