Atlantic Pharmaceuticals, Inc.

The University of Tennessee Research Foundation

Yichun Sun

Atul J Shukla

James R Johnson

Yingxu Peng

Anthony Edward Soscia

Robert Cooper

Gregg Boring

Dan Scruggs

A dosage form from which a burst release of a drug contained within a tampered dosage form is reduced or retarded by the presence in or on the dosage form of a TPTA (Tamper Prone Therapeutic Agent) trap. If the dosage form has not been tampered with, the TPTA trap does not significantly interfere with the rate of release of the drug from the dosage form. However, if the dosage form has been physically tampered with, the TPTA trap reduces or retards burst release of the drug from the dosage form.

Dosage forms for tamper prone therapeutic agents

A formulation containing one or more biologically active substances dissolved, dispersed, emulsified, or suspended within a vehicle of one or more citric acid esters and/or citric acid ethers. Methods for making and using are disclosed, as are kits for administration of the pharmaceutical formulation.

Vehicles for delivery of biologically active substances

Growing community of inventors

Germantown, TN, United States of America

Yichun Sun