Cartesian Therapeutics, Inc.

Yi Zhang

Murat V Kalayoglu

Michael S Singer

C Andrew Stewart

Metin Kurtoglu

Provided herein are chimeric antigen receptors (CARs), such as those specific for BCMA, that have improved properties, including increased CAR T cell binding to BCMA and improved CAR T cell killing of BCMA-expressing cancer cells. Use of the CARs in immune cells (e.g., T cells), compositions (e.g., CARs and nucleic acid constructs encoding the same), and methods are also contemplated.

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Gaithersburg, MD, United States of America

Yi Zhang