Lumeda Inc.

Other

Petrospec Engineering Ltd.

Yi Yang

Trevor Wayne MacDougall

In some implementations, the device may include an optical diffuser assembly having a plurality of light emitting devices positioned along an axis adjacent to one another and the plurality of light emitting devices are adapted to be selectively addressable to produce an irradiance pattern for each of the plurality of the light emitting devices.

Configurable optical applicator

A photodynamic therapy (PDT) apparatus and method are disclosed. The PDT apparatus includes a light flap that includes a plurality of light emitting devices wherein each of the light emitting devices has a plurality of operating states. The plurality of operating states are used to train a neural network model capable of producing a treatment irradiance profile. The method includes using an image of an area of interest for targeted treatment of PDT wherein the image is used an input to the trained neural network model. The neural network model produces a plurality of optimized feature states and the apparatus in turn produces a treatment irradiance profile closely matching the area of interest.

Optical applicator feature optimizer

A therapeutic light delivery apparatus and method are disclosed. The apparatus includes a light source, a plurality of light emitting devices paired with a plurality of light detecting devices, wherein each of the light emitting devices is in optical communication with a channel of a delivery optical switch and each of the plurality of light detection devices is in optical communication with a channel of a detection optical switch. The plurality of light emitting devices are fixedly positioned within an applicator light flap. The system further includes an optical detector in optical communication with the detector optical switch. The system further includes an opto-electronic controller that controls delivery optical switch, the detector optical switch and the light source.

Time mulitplexed dosimetry system and method

A therapeutic light delivery apparatus and method are disclosed. The apparatus includes a light source and an integrated optical applicator. The integrated optical applicator includes a plurality of light emitting devices and detector fibers fixedly spatially positioned within a flexible matrix material. The light emitting devices can be positioned a predetermined distance from an application side of the integrated optical applicator comprising an accurate and repeatable standoff position. A flexible matrix material is disclosed having a high scattering coefficient to produce a uniform irradiance pattern and predetermined fluence. A method of performing a photodynamic therapy procedure is disclosed that includes providing an integrated optical applicator couple to a therapy light source, providing a photosensitizing drug to a tissue of a patient, positioning an application side of the integrated optical applicator against a target area of the tissue, delivering a therapy light to the target area, and producing an irradiance pattern.

Optical surface applicator with integrated diffuser

Embodiments of the present disclosure include a low crosstalk, optical fiber based disturbance detection system that includes single-mode optical fiber (SMF) arranged into dual ring Sagnac interferometer wherein both rings share a common sensing section of optical fiber path length. Certain embodiments further include fiber Bragg gratings (FBG's), circulators and couplers to be able to separate the optical signals of the two rings of the dual ring Sagnac interferometer and to perform processing of their individual signals. Embodiments are also disclosed that enable the position of a physical disturbance, the magnitude of the physical disturbance and the frequency of the physical disturbance to be known.

Low crosstalk, common path, dual ring sagnac interferometer for disturbance sensing

An optical sensor apparatus illuminates nested optical cavities by a broadband light source, such as a tunable laser. A composite interference signal is obtained from light reflected from the nested optical cavities, partial interference spectra are recovered from the composite interference signal, cavity depths are measured based on the partial interference spectra, and electrical signals are provided based on the final measured cavity depths.

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Mansfield Storrs, CT, United States of America

Yi Yang