Massachusetts Institute of Technology

The General Hospital Corporation

Yi Yang

Marin Soljacic

Dirk Robert Englund

Simon Verghese

Jeffrey Scott Herd

Paul William Juodawlkis

Scott A Skirlo

Mihika Prabhu

Cheryl Marie Sorace-Agaskar

John Dimitris Joannopoulos

Brian Seed

Karl Kimon Berggren

Bo Zhen

Chia Wei Hsu

Charles Roques-Carmes

Ido Kaminer

Phillip Donald Keathley

Tena Dubcek

Nicholas H Rivera

Steven E Kooi

Emma Anquillare

Aviram Massuda

Yujia Yang

An integrated optical beam steering device includes a planar dielectric lens that collimates beams from different inputs in different directions within the lens plane. It also includes an output coupler, such as a grating or photonic crystal, that guides the collimated beams in different directions out of the lens plane. A switch matrix controls which input port is illuminated and hence the in-plane propagation direction of the collimated beam. And a tunable light source changes the wavelength to control the angle at which the collimated beam leaves the plane of the substrate. The device is very efficient, in part because the input port (and thus in-plane propagation direction) can be changed by actuating only logN of the N switches in the switch matrix. It can also be much simpler, smaller, and cheaper because it needs fewer control lines than a conventional optical phased array with the same resolution.

Methods and systems for optical beam steering

An apparatus for generating Smith-Purcell radiation having at least one spectral component at a wavelength &#x3bb; includes a periodic structure including a dielectric material and an electron source, in electromagnetic communication with the periodic structure, to emit an electron beam propagating within about 5&#x3bb; from a surface of the periodic structure to induce emission of the Smith-Purcell radiation. The electron beam has an electron energy tunable between about 0.5 keV and about 40 keV so as to change a wavelength of the Smith-Purcell radiation.

Apparatus and methods for generating and enhancing Smith-Purcell radiation

A transparent display includes nanoparticles having wavelength-selective scattering (e.g., resonant scattering) to preferentially scatter light at one or more discrete wavelengths so as to create images. The nanoparticles transmit light at other wavelengths to maintain a high transparency of the display. The nanoparticles are disposed in proximity to a thin film, which can enhance the scattering the process by reflecting light back to the nanoparticles for re-scattering or increasing the quality factor of the resonant scattering.

Transparent displays with scattering nanoparticles and thin films for enhanced scattering

The present invention features novel methods for generating cell lines and mammals with site-specific genetic modifications of interest. The methods involve homologous recombination between an artificial chromosome having a modification of interest and an endogenous chromosome of a cell. The resulting modified cells can be used in standard methods to generate genetically modified mammals. These mammals can be used in a variety of screening methods to identify compounds useful for the treatment or prevention of disease. Additionally, cells that have been modified to eliminate a mutation associated with a disease can be transplanted into patients for the treatment of a disease.

Methods for the production of cells and mammals with desired genetic modifications

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Cambridge, MA, United States of America

Yi Yang