Cfd Research Corporation

Yi Wang

Kapil Pant

Shivshankar Sundaram

Sivaramakrishnan Krishnamoorthy

Jianjun Feng

Guiren Wang

Balabhaskar Prabhakarpandian

Ketan Harendrakumar Bhatt

Balabhasker Prabhakarpandian

Hongjun Song

A micropump that pumps liquid using electrothermally-induced flow is described, along with a corresponding self-regulating pump and infusion pump. The micropump has applications in microfluidic systems, such as biochips. The self-regulating infusion pump is useful for administration of large and small volumes of liquids such as drugs to patients and can be designed for a wide range of flow rates by combining multiple micropumps in one infusion pump system. The micropump uses electrode sequences on opposing surfaces of a flow chamber that are staggered with respect to each other. The opposing surfaces include staggered electrodes that have the same phase and same electrode sequence. As such electrodes with the same phase are staggered and not eclipsed.

Miniaturized electrothermal flow induced infusion pump

An analyte selection device can include: a body defining a fluid channel having a channel inlet and channel outlet; a bipolar electrode (BPE) between the inlet and outlet; one of an anode or cathode electrically coupled with the BPE on a channel inlet side of the BPE and the other of the anode or cathode electrically coupled with the BPE on a channel outlet side of the BPE; and an electronic system operably coupled with the anode and cathode so as to polarize the BPE. The fluid channel can have any shape or dimension. The channel inlet and channel outlet can be longitudinal or lateral with respect to the longitudinal axis of the channel. The BPE can be any metallic member, such as a flat plate on a wall or mesh as a barrier BPE. The anode and cathode can be located at a position that polarizes the BPE.

Bipolar electrode sample preparation devices

A micropump that pumps liquid using electrothermally-induced flow is described, along with a corresponding self-regulating pump and infusion pump. The micropump has applications in microfluidic systems such as biochips. The self-regulating infusion pump is useful for the administration of large and small volumes of liquids such as drugs to patients and can be designed for a wide range of flow rates by combining multiple micropumps in one infusion pump system.

Particle separation apparatus separate particles and particle populations using dielectrophoretic (DEP) forces generated by one or more pairs of electrically coupled electrodes separated by a gap. Particles suspended in a fluid are separated by DEP forces generated by the at least one electrode pair at the gap as they travel over a separation zone comprising the electrode pair. Selected particles are deflected relative to the flow of incoming particles by DEP forces that are affected by controlling applied potential, gap width, and the angle linear gaps with respect to fluid flow. The gap between an electrode pair may be a single, linear gap of constant gap, a single linear gap having variable width, or a be in the form of two or more linear gaps having constant or variable gap width having different angles with respect to one another and to the flow.

Method and apparatus for separating particles by dielectrophoresis

An apparatus for concentrating aerosol particles can include: a sample air inlet; an enriched aerosol outlet; an aerosol lean outlet; a flow path connecting the air inlet and aerosol rich and aerosol lean outlets; and a plurality of alternately energized and grounded electrode pairs along the flow path. The aerosol rich outlet can be in fluid communication with an aerosol particle capture device. The apparatus can include a sheath air inlet providing a flow of aerosol free air over surfaces of the alternately energized and grounded electrode pairs. The apparatus can include an elongate focusing chamber having a cylindrical shape containing the alternately energized and grounded electrode pairs that are configured as circular rings. The apparatus can include one or more structures configured to impart tangential, spiral or helical flow to a stream entering through the sample air inlet.

Electrostatic aerosol concentrator

A microfluidic cartridge for isolating biological molecules having a capture chamber containing functionalized solid supports maintained in a fluidized state provides reduced pressure drops and bubble formation during microfluidic extraction. The cartridge may include an electric field lysis chamber and/or a chemical lysis chamber. The electric-field lysis chamber may comprise an electrically insulating structure arranged between two opposing planar electrodes.

Microfluidic biological extraction chip

An electrostatic aerosol concentrator includes an airflow chamber with alternately energized and grounded electrode elements that work in concert to impart radial inward motion to charged aerosol particles and focusing them toward an enriched aerosol outlet. Aerosol particles entering the airflow chamber may carry a positive or negative charge naturally, or a charge may be induced on the particles using a charging section located upstream of the aerosol inlet. Natural or induced charges on the aerosol particles may be used to selectively concentrate subpopulations of aerosol particles from a mixture of particles. For example, bacterial spores or aerosolized viruses may be selectively enriched without concentrating other aerosol particles.

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Madison, AL, United States of America

Yi Wang