Industrial Technology Research Institute

Yi-Ting Hsieh

Yu-Chun Liu

Jing-Wen Tang

Ting-Yu Shih

Lu-Chih Wang

Yuan-Kun Yu

Hsiang-Fa Liang

Jui-Hsiang Chen

Chih-Peng Liu

Ming-Cheng Wei

Shu-Fang Chiang

Chia-Mu Tu

Maggie J M Lu

Min-Ying Lin

Ya-Chin Lo

Hsiang-Wen Tseng

Chun-Min Liu

Tse-Min Teng

Chia-Chun Wang

Yi-Man Chou

A graft polymer is provided, which includes a polymer backbone with a plurality of hydroxy groups, protection group modified histidine grafted onto the side of the polymer backbone, and hydrophilic polymer having terminal reactive group grafted onto the side of the polymer backbone. The graft polymer coating can be applied to metal material to form a composite material, which can be implanted into an organism to reduce adhesion problems.

Graft polymer and composite material containing the same

A method for skin care and/or maintenance including applying or administering a preparation to a subject is provided. The preparation includes a biomedical composition, and the biomedical composition includes an effective amount of micelle, wherein the micelle includes a hyaluronic acid and/or a derivative thereof and a modified histidine. The modified histidine is grafted to at least one primary hydroxyl group of the hyaluronic acid and/or the derivative thereof, and a graft ratio of the modified histidine is 1-100%. Moreover, the hyaluronic acid and/or the derivative thereof and the modified histidine form the micelle on a weight percentage of 0.2-300:1.

Biomedical composition for skin care and/or maintenance and delaying and/or inhibiting skin aging and the use thereof

The disclosure provides a biomedical composition, including: a hyaluronic acid; a modified histidine; and a polymer or C-Calkane, wherein the modified histidine and the polymer or C-Calkane are grafted to at least one primary hydroxyl group of the hyaluronic acid to allow the hyaluronic acid to form a hyaluronic acid derivative, wherein a graft ratio of the modified histidine is about 1-100%, and a graft ratio of the polymer or C-Calkane is about 0-40%.

Biomedical composition

Growing community of inventors

Zhudong, Taiwan

Yi-Ting Hsieh