Mayo Foundation for Medical Education and Research

Yi Sui

Richard L Ehman

Joshua D Trzasko

John Huston, Iii

Matthew A Bernstein

Meng Yin

Philip A Araoz

Arvin Forghanian-Arani

Uten Yarach

Myung-Ho In

Ziying Yin

Described here are systems and methods for a robust magnetic resonance elastography ('MRE') imaging platform for rapid dynamic 3D MRE imaging. The imaging platform includes an MRE pulse sequence and advanced image reconstruction framework that work synergistically in order to greatly expand the domains where MRE can be deployed successfully.

Continuous three-dimensional imaging for magnetic resonance elastography

Nyquist ghost artifacts in echo planar imaging ('EPI') are mitigated, reduced, or otherwise eliminated by implementing robust Nyquist ghost correction (“NGC”) directly from two reversed readout EPI acquisitions. As one advantage, these techniques do not require explicit reference scanning. A model-based process is used for directly estimating statistically optimal NGC coefficients from multi-channel k-space data.

Model-based Nyquist ghost correction for reverse readout echo planar imaging

Described here are systems and methods for evaluating the extent of brain-skull tethering, which may also be referred to as loss of trabecular reserve, in subjects using magnetic resonance elastography ('MRE'). The present disclosure describes a method for assessing progressive damage to arachnoid space ('SAS') trabeculae. The method generally includes measuring the relative movement between the brain and the skull using MRE. As one example, an MRE-based method named slip interface imaging (&#x201c;SII&#x201d;) can be implemented. By measuring trabecular reserve in subjects who have a history of prior head trauma, the susceptibility of a given subject to future injury can be assessed.

Methods for quantifying trabecular reserve using magnetic resonance elastography

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Rochester, MN, United States of America

Yi Sui