Cspc Zhongqi Pharmaceutical Technology (shijiazhuang) Co., Ltd.

Peking University

Hebei Medical University

Cspc Zhongqi Pharmaceutical Technology Co., Ltd.

Yi Mi

Ying Shi

Qingzhi Gao

Hanyu Yang

Yujie Chen

Yuxiu Ma

Xiaozhuo Chen

Dongmin Shen

Guorui Mi

Yang Guo

Linjing Fan

Xuliang Wang

Yaran Zhang

Chunlei Liu

Wen Xu

Kewei Wang

Xuejiao Zhang

Min Bai

Jinlong Qi

Fan Zhang

Qingzhong Jia

Xiaona Du

Hailin Zhang

Denghuang Gong

Diqun Zhang

Yan Fu

Yibing Wu

Shuangge Yang

Provided are a quinazoline derivative, a pharmaceutical composition containing the same, a method for preparation of said derivative, and an application of same as an anti-cancer drug. 

Quinazoline derivative

The present invention relates to a benzamide derivative of general formula I, a drug composition containing same and a use thereof as a drug, wherein the definitions of R, Z and Q are as described in the description. 

Benzamide derivative

Disclosed are a compound of formula (I), a tautomer, an optical isomer or a pharmaceutically acceptable salt thereof, and a pharmaceutical composition containing the above-mentioned compounds. The above-mentioned compounds have the activity of inhibiting Xa factor positive effect, and can be used for the preparation of a medicament for preventing and/or treating diseases inhibiting Xa factor positive effect in case of low bleeding risk. 

Pyrazolo[3,4-c]pyridine derivatives

The present invention provides new pyrazol-[1,5-a]-pyrimidone derivates and pharmaceutical compositions comprising said compounds and one or more pharmaceutically acceptable carriers or diluents. The uses of the compounds for the manufacture of potassium channel openers, anti-epilepsy medicaments, anti-anxiety medicaments and analgesic medicaments are also provided in the present invention.

Pyrazolo [1,5-a]-pyrimidones derivatives and pharmaceutical compositions and uses thereof

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Shijiazhuang, China

Yi Mi