Academia Sinica

Academic Sinica

Yi-Jen Huang

An-Suei Yang

Chung-Ming Yu

Ing-Chien Chen

Yu-Ching Lee

Keng-Chang Tsai

Hung-Ju Hsu

Hung-Pin Peng

Hung-Ju Chang

Cheng-Chung Lee

Hong-Sen Chen

Hwei-Jiung Wang

Chao-Ping Tung

Yi-Kai Chiu

Yueh-Liang Tsou

Chia-Lung Lin

Disclosed herein are methods for high-throughput screening of a virus-specific neutralizing antibody. According to certain embodiments of the present disclosure, the virus is an influenza virus. Also disclosed herein are the antibodies selected by the high-throughput screening method, and the uses thereof in the prophylaxis and/or treatment of viral infection.

Method for high-throughput screening of neutralizing antibodies, neutralizing antibodies produced therefrom, and uses thereof

Disclosed are nucleic acid libraries for identifying a signal peptide that facilitates production of disulfide-stabilized single chain antibody, and for facilitating production of a disulfide-stabilized single chain antibody. Also disclosed are host cell libraries and phage libraries including the nucleic acid libraries. Further disclosed are methods for identifying a signal peptide that facilitates production of disulfide-stabilized single chain antibody, and methods for producing a disulfide-stabilized single chain antibody and non-fusion form thereof.

Phage displaying system expressing single chain antibody

Growing community of inventors

Taipei, Taiwan

Yi-Jen Huang