Kaohsiung Medical University

Metal Industries Research & Development Centre

We-win Bio-medical Co., Ltd.

Yi-Hong Tsai

Fang-Rong Chang

Yang-Chang Wu

Ying-Chi Du

Tusty-Jiuan Hsieh

Tsong-Long Hwang

Chin-Chung Wu

Tzu-Chen Kuo

Shih-Wei Wang

Pei-Jung Lien

Hui-Ping Hsieh

Sheng-Chung Yang

Bing-Hung Chen

Chen Hsieh

Chuan-Chia Sun

Kartiko Arif Purnomo

Yen-chang Chen

Chia-Hua Liang

Chi-Ting Hsieh

A use of extracts of roselle seeds for preparing a composition of antioxidant, anti-inflammation, anti-UVB, anti-allergy, whitening, moisturizing, and anti-wrinkle, wherein the extracts of the roselle seeds comprise lauric, palmitic, linoleic, oleic, or stearic acids; and a method for preparing the extracts of the roselle seeds comprises steps of: steeping of: extracting a weight ratio of the 12:1 to 20:1 roselle seeds and an ethanol solution with a concentration of 75 to 95%; and steeping the roselle seeds in the ethanol solution to obtain a suspension; and extraction of: the suspension being engaged in an extraction of a continuous and rapid oscillation with an ultrasonic energy with a total energy of 200 to 500W, wherein 1 to 3 hours of the oscillation is one cycle, and a total number of 3 to 5 cycles is lasted, in order to obtain roselle seed crude extracts.

Antioxidant, anti-inflammatory, ANTI-UVB, anti-allergic, whitening, and anti-wrinkle roselle seed extract

The present invention relates to a maca extract and uses thereof. The part of the maca extract extracted with polar solvent has anti-thrombotic activity, the part of the maca extract extracted with medium and low polarity solvents has anti-neutrophilic inflammatory and anti-allergic activities, the part of the maca extract extracted with low polarity solvent has anti-neutrophilic inflammatory activity and has pro-angiogenic activity.

Maca extract and use thereof

Theextract of the present invention is prepared using supercritical fluid technique, wherein the method includes steps of: (a) drying the leaves of; (b) pulverizing the leaves as particles; and (c) extracting the particles with supercritical carbon dioxide to obtain theextract. This supercriticalextract not only can decrease blood sugar level, but also promotes lipid degradation, inhibits the formation of huge lipid droplet and improves the metabolic symptoms. Accordingly, theextract further is able to be prepared as food supplement and pharmaceuticals.

Extract offrom supercritical fluid extraction for treating diabetes and metabolic disease, the preparation method and the use thereof

Disclosed is a chalcone composition for treating diabetes and metabolic syndromes. In particular, the chalcone compound bound with 2-halogen in ring A significantly decreases the blood glucose level in the in vitro anti-diabetic effect experiment. In the in vivo animal model, the leading chalcone compound can prevent the progression of diabetes and control the blood glucose level, and there is no significant difference in the gains in body weight. Throughout the seven-week administration, there are no hepatic or renal toxicity observed.

Composition for treating diabetes and metabolic diseases and a preparation method thereof

Growing community of inventors

Kaohsiung, Taiwan

Yi-Hong Tsai