University of Toronto

Yi-Chen Cathy Huang

Dennis G Cvitkovitch

Celine Levesque

Compounds that competitively inhibit binding of CSP tohistidine kinase are provided. The compounds are preferably a peptide or an antibody, and are preferably a derivative of [SEQ ID NO:2], a fragment of [SEQ ID NO:2] or a derivative of a fragment of [SEQ ID NO:2]. Methods of making these compounds and their use for inhibiting the growth of, for inhibiting dental caries, and for improving dental health are also disclosed.

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Toronto, Canada

Yi-Chen Cathy Huang