Emergex USA Corporation

Zosano Pharma Corporation

Zp Opco, Inc.

Medimmune Limited

Yi Ao

Mahmoud Ameri

Peter E Daddona

Donald Kellerman

Reinhard Vehring

Peter C Schmidt

Compositions, devices and methods employing therapeutic concentrations of a triptan for treatment of migraine are described. Also described are methods and apparatuses for delivery of zolmitriptan for achieving a Tas quick as 2 minutes and not later than 30 minutes in the majority of subjects.

Method of rapidly achieving therapeutic concentrations of triptans for treatment of migraines

Method of rapidly achieving therapeutic concentrations of triptans for treatment of migraines and cluster headaches

Compositions, devices and methods employing therapeutic concentrations of a triptan for treatment of migraine are described. Also described are methods for treating migraine by administering zolmitriptan using an adhesive dermally-applied microarray (ADAM) resulting in rapid and durable pain relief, pain freedom and reduction in most bothersome migraine-associated symptoms (MBS), or a combination thereof.

There is provided glucagon formulations suitable for preparing coatings on microneedle patches for the transdermal delivery of glucagon. The coated patches may be used for the treatment of low blood sugar in diabetic patients. Also provided are glucagon loaded patches, methods for their preparation, and methods of their use.

Stable glucagon peptide formulations

This invention provides methods, systems and compositions to preserve bioactive materials in a dried foam matrix. Methods provide non-boiling foam generation and penetration of preservative agents at temperatures near the phase transition temperature of the membranes. Bioactive materials can be preserved with high initial viability in a freeze-foam process employing low temperature secondary drying.

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Palo Alto, CA, United States of America

Yi Ao